5,6-Di-O-benzyl-D-glucofuranose

Base Information

• Chemical Name: 5,6-Di-O-benzyl-D-glucofuranose
• CAS No.: 94686-95-0
• Molecular Formula: C₂₀H₂₄O₆
• Molecular Weight: 360.407
• Mol file: 94686-95-0.mol

Synonyms:5,6-Di-O-benzyl-D-glucofuranose

Chemical Property of 5,6-Di-O-benzyl-D-glucofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,6-Di-O-benzyl-D-glucofuranose

There total 8 articles about 5,6-Di-O-benzyl-D-glucofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C21H26O6 → 5,6-Di-O-benzyl-D-glucofuranose (94686-95-0)

Guidance literature:

With hydrogenchloride; water; In 1,4-dioxane; at 90 ℃; for 5h;

DOI:10.1016/j.tet.2012.06.105

Reference yield:

C22H36O6Si (142719-12-8) → 5,6-Di-O-benzyl-D-glucofuranose (94686-95-0)

Guidance literature:

Multi-step reaction with 5 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 23 h / 0 - 20 °C

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 4.5 h / 20 °C

3: sodium hydride / tetrahydrofuran; mineral oil / 17 h / 0 - 20 °C

4: hydrogenchloride / water / 3 h / 0 - 50 °C

5: hydrogenchloride; water / 1,4-dioxane / 5 h / 90 °C

With hydrogenchloride; tetrabutyl ammonium fluoride; water; sodium hydride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; mineral oil;

DOI:10.1016/j.tet.2012.06.105

Reference yield:

C24H40O7Si (1394245-86-3) → 5,6-Di-O-benzyl-D-glucofuranose (94686-95-0)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4.5 h / 20 °C

2: sodium hydride / tetrahydrofuran; mineral oil / 17 h / 0 - 20 °C

3: hydrogenchloride / water / 3 h / 0 - 50 °C

4: hydrogenchloride; water / 1,4-dioxane / 5 h / 90 °C

With hydrogenchloride; tetrabutyl ammonium fluoride; water; sodium hydride; In tetrahydrofuran; 1,4-dioxane; water; mineral oil;

DOI:10.1016/j.tet.2012.06.105

upstream raw materials:

benzyl chloride

C₂₂H₃₆O₆Si

C₂₄H₄₀O₇Si

C₂₅H₃₂O₇

Downstream raw materials:

C₂₀H₂₂O₆