(3R,5S)-1-{2-cyclohexyl-2-[(2R)-oct-7-en-2-ylamino]acetyl}-5-(methoxycarbonyl)pyrrolidin-3-yl 4-ethenyl-1,3-dihydro-2H-isoindole-2-carboxylate

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Chemical Name:(3R,5S)-1-{2-cyclohexyl-2-[(2R)-oct-7-en-2-ylamino]acetyl}-5-(methoxycarbonyl)pyrrolidin-3-yl 4-ethenyl-1,3-dihydro-2H-isoindole-2-carboxylate
CAS No.:1000064-10-7
Molecular Formula:C₃₃H₄₇N₃O₅
Molecular Weight:565.753
Hs Code.:

Synonyms:(3R,5S)-1-{2-cyclohexyl-2-[(2R)-oct-7-en-2-ylamino]acetyl}-5-(methoxycarbonyl)pyrrolidin-3-yl 4-ethenyl-1,3-dihydro-2H-isoindole-2-carboxylate

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Chemical Property of (3R,5S)-1-{2-cyclohexyl-2-[(2R)-oct-7-en-2-ylamino]acetyl}-5-(methoxycarbonyl)pyrrolidin-3-yl 4-ethenyl-1,3-dihydro-2H-isoindole-2-carboxylate

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Technology Process of (3R,5S)-1-{2-cyclohexyl-2-[(2R)-oct-7-en-2-ylamino]acetyl}-5-(methoxycarbonyl)pyrrolidin-3-yl 4-ethenyl-1,3-dihydro-2H-isoindole-2-carboxylate

There total 1 articles about (3R,5S)-1-{2-cyclohexyl-2-[(2R)-oct-7-en-2-ylamino]acetyl}-5-(methoxycarbonyl)pyrrolidin-3-yl 4-ethenyl-1,3-dihydro-2H-isoindole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 923672-39-3
C₁₇H₂₀N₂O₄

: 1000064-09-4
(2S)-cyclohexyl[oct-7-en-2-ylamino]ethanoic acid

: 1000064-10-7
(3R,5S)-1-{2-cyclohexyl-2-[(2R)-oct-7-en-2-ylamino]acetyl}-5-(methoxycarbonyl)pyrrolidin-3-yl 4-ethenyl-1,3-dihydro-2H-isoindole-2-carboxylate

Guidance literature:: (2S)-cyclohexyl[oct-7-en-2-ylamino]ethanoic acid; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In dichloromethane;

C₁₇H₂₀N₂O₄; In dichloromethane;
DOI:10.1021/jm900372w

Reference yield: 31.0%

: 1000064-10-7
(3R,5S)-1-{2-cyclohexyl-2-[(2R)-oct-7-en-2-ylamino]acetyl}-5-(methoxycarbonyl)pyrrolidin-3-yl 4-ethenyl-1,3-dihydro-2H-isoindole-2-carboxylate

: 76-05-1
trifluoroacetic acid

: 1179843-06-1
(5R,7S,10S,12R,17E)-10-cyclohexyl-7-(methoxycarbonyl)-12-methyl-3,9-dioxo-6,7,9,10,11,12,13,14,15,16-decahydro-1H,5H-2,22:5,8-dimethano-4,2,8,11-benzoxatriazacycloicosin-11-ium trifluoroacetate

: (5R,7S,10S,12S,17E)-10-cyclohexyl-7-(methoxycarbonyl)-12-methyl-3,9-dioxo-6,7,9,10,11,12,13,14,15,16-decahydro-1H,5H-2,22:5,8-dimethano-4,2,8,11-benzoxatriazacycloicosin-11-ium trifluoroacetate

Guidance literature:: (3R,5S)-1-{2-cyclohexyl-2-[(2R)-oct-7-en-2-ylamino]acetyl}-5-(methoxycarbonyl)pyrrolidin-3-yl 4-ethenyl-1,3-dihydro-2H-isoindole-2-carboxylate; With [1,3-bis-(2,4,6-trimethylphenyl)imidazolidin-2-yl]-(dichloro)[5-chloro-2-(propan-2-yloxy)benzylidene]ruthenium; In dichloromethane; at 100 ℃; Microwave irradiation;

trifluoroacetic acid; In water; acetonitrile;
DOI:10.1021/jm900372w