3(2H)-Isoquinolinone, 1,4-dihydro-2-amino-

Base Information

Chemical Name:3(2H)-Isoquinolinone, 1,4-dihydro-2-amino-
CAS No.:39113-02-5
Molecular Formula:C9H10N2O
Molecular Weight:162.1885
Hs Code.:
DSSTox Substance ID:DTXSID30192361
Nikkaji Number:J68.855J
Wikidata:Q83065017
Mol file:39113-02-5.mol

Synonyms:3(2H)-Isoquinolinone, 1,4-dihydro-2-amino-;BRN 1452401;39113-02-5;2-Amino-1,4-dihydro-3(2H)-isoquinolinone;2-Amino-1,4-diidroisochinolin-3(2H)-one [Italian];2-Amino-1,4-diidroisochinolin-3(2H)-one;3(2H)-Isoquinolinone, 2-amino-1,4-dihydro-;5-21-08-00075 (Beilstein Handbook Reference);2-amino-1,4-dihydroisoquinolin-3-one;2-amino-1,4-dihydroisoquinolin-3(2h)-one;SCHEMBL13806435;BDBM23988;DTXSID30192361;N-Substituted dihydro-isoquinolinone, 4d;LS-86203;1,4-Dihydro-2-aminoisoquinolin-3(2H)-one;2-amino-1,2,3,4-tetrahydroisoquinolin-3-one

Suppliers and Price of 3(2H)-Isoquinolinone, 1,4-dihydro-2-amino-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3(2H)-Isoquinolinone, 1,4-dihydro-2-amino-

Chemical Property:

Vapor Pressure:0.000309mmHg at 25°C
Boiling Point:320.9°C at 760 mmHg
Flash Point:147.9°C
Density:1.234g/cm³
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:162.079312947
Heavy Atom Count:12
Complexity:193

Purity/Quality:: 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=CC=CC=C2CN(C1=O)N

Technology Process of 3(2H)-Isoquinolinone, 1,4-dihydro-2-amino-

There total 5 articles about 3(2H)-Isoquinolinone, 1,4-dihydro-2-amino- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 13737-37-6
methyl 2-[2-(bromomethyl)phenyl]acetate

: 39113-02-5
2-amino-1,4-dihydroisoquinolin-3(2H)-one

Guidance literature:: With hydrazine dihydrochloride; sodium carbonate; In methanol; at 80 ℃; for 48h;
DOI:10.1016/j.bmc.2006.06.050

Reference yield:

: 13737-35-4
o-(bromomethyl)phenylacetic acid

: 39113-02-5
2-amino-1,4-dihydroisoquinolin-3(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: HCl / diethyl ether

2: 70 percent / hydrazine dihydrochloride; sodium carbonate / methanol / 48 h / 80 °C

With hydrogenchloride; hydrazine dihydrochloride; sodium carbonate; In methanol; diethyl ether;
DOI:10.1016/j.bmc.2006.06.050