Technology Process of 4-azidophenyl tosylate
There total 4 articles about 4-azidophenyl tosylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-aminophenyl-4-toluenesulfonic acid ester;
With
hydrogenchloride; sodium nitrite;
In
water; acetic acid;
at 0 ℃;
for 0.166667h;
With
sodium azide;
In
water; acetic acid;
at 0 ℃;
for 1h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 73 percent / stannous chloride dihydrate; hydrochloric acid / H2O / 2 h / Heating
2.1: hydrochloric acid; sodium nitrite / H2O; acetic acid / 0.17 h / 0 °C
2.2: 90 percent / sodium azide / H2O; acetic acid / 1 h / 0 °C
With
hydrogenchloride; tin(ll) chloride; sodium nitrite;
In
water; acetic acid;
1.1: Reduction / 2.1: Diazotization / 2.2: Substitution;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 70 percent / triethylamine / CH2Cl2 / 0.5 h / 20 °C
2.1: hydrochloric acid; sodium nitrite / H2O; acetic acid / 0.17 h / 0 °C
2.2: 90 percent / sodium azide / H2O; acetic acid / 1 h / 0 °C
With
hydrogenchloride; triethylamine; sodium nitrite;
In
dichloromethane; water; acetic acid;
1.1: Tosylation / 2.1: Diazotization / 2.2: Substitution;
