ethyl 4-[2-(2-{[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino}-1-hydroxy-ethyl)-3-thienyl]benzoate

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Chemical Name:ethyl 4-[2-(2-{[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino}-1-hydroxy-ethyl)-3-thienyl]benzoate
CAS No.:1148012-20-7
Molecular Formula:C₂₈H₃₃NO₃S
Molecular Weight:463.641
Hs Code.:

Synonyms:ethyl 4-[2-(2-{[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino}-1-hydroxy-ethyl)-3-thienyl]benzoate

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Chemical Property of ethyl 4-[2-(2-{[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino}-1-hydroxy-ethyl)-3-thienyl]benzoate

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Technology Process of ethyl 4-[2-(2-{[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino}-1-hydroxy-ethyl)-3-thienyl]benzoate

There total 1 articles about ethyl 4-[2-(2-{[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino}-1-hydroxy-ethyl)-3-thienyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 1148012-03-6
1-(3-bromo-2-thienyl)-2-{[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino}ethanol

: 4334-88-7
p-ethoxycarbonylphenylboronic acid

: 1148012-20-7
ethyl 4-[2-(2-{[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino}-1-hydroxy-ethyl)-3-thienyl]benzoate

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; water; toluene; at 20 - 80 ℃; for 12h;

Reference yield: 57.0%

: 1148012-20-7
ethyl 4-[2-(2-{[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino}-1-hydroxy-ethyl)-3-thienyl]benzoate

: 1148012-19-4
4-[2-(2-{[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino}-1-hydroxyethyl)-3-thienyl]benzoic acid

Guidance literature:: ethyl 4-[2-(2-{[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino}-1-hydroxy-ethyl)-3-thienyl]benzoate; With methanol; lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 1h;

With hydrogenchloride; water; pH=6;