2-(4-benzyloxy-3-ethyl-5-methyl-phenyl)-5-(4-isopropoxy-3-methyl-phenyl)-[1,3,4]oxadiazole

Base Information

Chemical Name:2-(4-benzyloxy-3-ethyl-5-methyl-phenyl)-5-(4-isopropoxy-3-methyl-phenyl)-[1,3,4]oxadiazole
CAS No.:1014691-19-0
Molecular Formula:C₂₈H₃₀N₂O₃
Molecular Weight:442.558
Hs Code.:

Synonyms:2-(4-benzyloxy-3-ethyl-5-methyl-phenyl)-5-(4-isopropoxy-3-methyl-phenyl)-[1,3,4]oxadiazole

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Chemical Property of 2-(4-benzyloxy-3-ethyl-5-methyl-phenyl)-5-(4-isopropoxy-3-methyl-phenyl)-[1,3,4]oxadiazole

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Technology Process of 2-(4-benzyloxy-3-ethyl-5-methyl-phenyl)-5-(4-isopropoxy-3-methyl-phenyl)-[1,3,4]oxadiazole

There total 11 articles about 2-(4-benzyloxy-3-ethyl-5-methyl-phenyl)-5-(4-isopropoxy-3-methyl-phenyl)-[1,3,4]oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1014691-18-9
4-benzyloxy-3-ethyl-5-methyl-benzoic acid N'-(4-isopropoxy-3-methyl-benzoyl)hydrazide

: 1014691-19-0
2-(4-benzyloxy-3-ethyl-5-methyl-phenyl)-5-(4-isopropoxy-3-methyl-phenyl)-[1,3,4]oxadiazole

Guidance literature:: With Burgess Reagent; In tetrahydrofuran; at 110 ℃; for 0.05h; Microwave irradiation;

Reference yield:

: 856165-81-6
4-isopropoxy-3-methylbenzoyl chloride

: 1014691-19-0
2-(4-benzyloxy-3-ethyl-5-methyl-phenyl)-5-(4-isopropoxy-3-methyl-phenyl)-[1,3,4]oxadiazole

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / chloroform / 2 h / Heating / reflux

2: triethylamine / dichloromethane / 1 h / 20 °C

3: Burgess Reagent / tetrahydrofuran / 0.05 h / 110 °C / Microwave irradiation

With thionyl chloride; Burgess Reagent; triethylamine; In tetrahydrofuran; dichloromethane; chloroform;

Reference yield:

: 854631-20-2
4-isopropoxy-3-methylbenzoyl chloride

: 1014691-19-0
2-(4-benzyloxy-3-ethyl-5-methyl-phenyl)-5-(4-isopropoxy-3-methyl-phenyl)-[1,3,4]oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 1 h / 20 °C

2: Burgess Reagent / tetrahydrofuran / 0.05 h / 110 °C / Microwave irradiation

With Burgess Reagent; triethylamine; In tetrahydrofuran; dichloromethane;