D-altro-Heptulose

Base Information

• Chemical Name: D-altro-Heptulose
• CAS No.: 3019-74-7
• Molecular Formula: C7H14 O7
• Molecular Weight: 210.184
• Hs Code.: 2914400090
• DSSTox Substance ID: DTXSID10952581
• Metabolomics Workbench ID: 68548
• Mol file: 3019-74-7.mol

Synonyms:D-altro-Heptulose;C02076;Volemulose;AC1L97R2;Hept-2-ulopyranose;SureCN7156313;SCHEMBL7156313;DTXSID10952581;(3S,4R,5S,6R)-2,6-bis(hydroxymethyl)oxane-2,3,4,5-tetrol;(3S,4R,5S,6R)-2,6-bis(hydroxymethyl)tetrahydropyran-2,3,4,5-tetrol

Chemical Property of D-altro-Heptulose

Chemical Property:

• Vapor Pressure: 2.08E-18mmHg at 25°C
• Melting Point: 249 °C
• Refractive Index: 1.597
• Boiling Point: 628°Cat760mmHg
• PKA: 11.86±0.20(Predicted)
• Flash Point: 347.6°C
• PSA: 138.45000
• Density: 1.645g/cm³
• LogP: -4.01630
• Storage Temp.: 2-8°C
• XLogP3: -2.9
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 210.07395278
• Heavy Atom Count: 14
• Complexity: 199

Purity/Quality:

98%,99%, ^*data from raw suppliers

D-Sedoheptulose ≥95% (TLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C1C(C(C(C(O1)(CO)O)O)O)O)O
• Isomeric SMILES: C([C@@H]1[C@H]([C@H]([C@@H](C(O1)(CO)O)O)O)O)O

Technology Process of D-altro-Heptulose

There total 23 articles about D-altro-Heptulose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

D-ribose (50-69-1) + Lithium hydroxypyruvate (3369-79-7) → sedoheptulose (3019-74-7)

Guidance literature:

With water; thiamine diphosphate; 1-butyl-3-methylimidazolium chloride; magnesium chloride; at 25 ℃; pH=7.5; Reagent/catalyst; Enzymatic reaction;

DOI:10.1002/cctc.201500524

Reference yield: 75.0%

D-Serine (312-84-5,83245-15-2) + D-ribose (50-69-1) → sedoheptulose (3019-74-7)

Guidance literature:

With magnesium(II) chloride hexahydrate; flavin adenine dinucleotide (FAD)-containing flavoenzyme from the yeast Rhodotorula gracilis; thiamine pyrophosphate; oxygen; In water; at 25 ℃; for 32h; pH=7; Enzymatic reaction;

DOI:10.1002/adsc.201900109

Reference yield: 70.0%

3-hydroxy-2-oxopropionic acid (1113-60-6) + D-ribose (50-69-1) → sedoheptulose (3019-74-7)

Guidance literature:

With thiamine pyrophosphate; magnesium chloride; at 25 ℃; spinach transketolase, pH 7.5;

DOI:10.1016/S0957-4166(00)80225-6

upstream raw materials:

Hexa-O-acetyl-α-D-altro-[2]heptulopyranose

D-altronic acid

3-hydroxy-2-oxopropionic acid

D-ribose

Downstream raw materials:

gluco-[2]heptosulose-bis-phenylhydrazone

volemitol

D-glycero-D-gluco-heptitol

sedoheptulosan

Refernces

• 1、 Ranoux, Adeline,Arends, Isabel W.C.E.,Hanefeld, Ulf. "Development of screening methods for transketolase activity and substrate scope". . p. 790 - 793. Retrieved 2012.
• 2、 Bevenue,Williams. "". . p. 391,392-395. Retrieved 1960.
• 3、 Dalmas,Demuynck. "An efficient synthesis of sedoheptulose catalyzed by spinach transketolase". . p. 1169 - 1172. Retrieved 1993.
• 4、 Ali, Ghina,Moreau, Thomas,Forano, Claude,Mousty, Christine,Prevot, Vanessa,Charmantray, Franck,Hecquet, Laurence. "Chiral Polyol Synthesis Catalyzed by a Thermostable Transketolase Immobilized on Layered Double Hydroxides in Ionic liquids". . p. 3163 - 3170. Retrieved 2015/10/19.