Methyl <2S-<1*<1R^*,1(E),2S^*>>,2α,5β>>-1-(4,8-Dimethyl-3,7-nonadienyl)-2-<1-<(2,5-dimethyl-1-pyrrolidinyl)carbonyl>-4-(phenylmethoxy)butyl>cyclopentanecarboxylate

Base Information

• Chemical Name: Methyl <2S-<1*<1R^*,1(E),2S^*>>,2α,5β>>-1-(4,8-Dimethyl-3,7-nonadienyl)-2-<1-<(2,5-dimethyl-1-pyrrolidinyl)carbonyl>-4-(phenylmethoxy)butyl>cyclopentanecarboxylate
• CAS No.: 129539-97-5
• Molecular Formula: C₃₆H₅₅NO₄
• Molecular Weight: 565.837
• Mol file: 129539-97-5.mol

Synonyms:Methyl <2S-<1*<1R^*,1(E),2S^*>>,2α,5β>>-1-(4,8-Dimethyl-3,7-nonadienyl)-2-<1-<(2,5-dimethyl-1-pyrrolidinyl)carbonyl>-4-(phenylmethoxy)butyl>cyclopentanecarboxylate

Chemical Property of Methyl <2S-<1*<1R^*,1(E),2S^*>>,2α,5β>>-1-(4,8-Dimethyl-3,7-nonadienyl)-2-<1-<(2,5-dimethyl-1-pyrrolidinyl)carbonyl>-4-(phenylmethoxy)butyl>cyclopentanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl <2S-<1*<1R^*,1(E),2S^*>>,2α,5β>>-1-(4,8-Dimethyl-3,7-nonadienyl)-2-<1-<(2,5-dimethyl-1-pyrrolidinyl)carbonyl>-4-(phenylmethoxy)butyl>cyclopentanecarboxylate

There total 5 articles about Methyl <2S-<1*<1R^*,1(E),2S^*>>,2α,5β>>-1-(4,8-Dimethyl-3,7-nonadienyl)-2-<1-<(2,5-dimethyl-1-pyrrolidinyl)carbonyl>-4-(phenylmethoxy)butyl>cyclopentanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(phenylmethoxy)pentanoic acid chloride (128329-72-6) → Methyl <2S-<1*<1R*,1(E),2S*>>,2α,5β>>-1-(4,8-Dimethyl-3,7-nonadienyl)-2-<1-<(2,5-dimethyl-1-pyrrolidinyl)carbonyl>-4-(phenylmethoxy)butyl>cyclopentanecarboxylate (129539-97-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 2 N NaOH / diethyl ether / 1 h / Ambient temperature

With sodium hydroxide; In diethyl ether;

DOI:10.1021/jo00035a010

Reference yield:

5-benzyloxypentanoic acid (64740-39-2) → Methyl <2S-<1*<1R*,1(E),2S*>>,2α,5β>>-1-(4,8-Dimethyl-3,7-nonadienyl)-2-<1-<(2,5-dimethyl-1-pyrrolidinyl)carbonyl>-4-(phenylmethoxy)butyl>cyclopentanecarboxylate (129539-97-5)

Guidance literature:

Multi-step reaction with 3 steps

1: oxalyl chloride / CH₂Cl₂

2: 2 N NaOH / diethyl ether / 1 h / Ambient temperature

With sodium hydroxide; oxalyl dichloride; In diethyl ether; dichloromethane;

DOI:10.1021/jo00035a010

Reference yield:

(2S,5S)-2,5-dimethylpyrrolidine (117968-50-0) → Methyl <2S-<1*<1R*,1(E),2S*>>,2α,5β>>-1-(4,8-Dimethyl-3,7-nonadienyl)-2-<1-<(2,5-dimethyl-1-pyrrolidinyl)carbonyl>-4-(phenylmethoxy)butyl>cyclopentanecarboxylate (129539-97-5)

Guidance literature:

Multi-step reaction with 2 steps

1: Schotten-Baumann conditions

DOI:10.1021/jo00307a006

upstream raw materials:

1-(carboxymethoxy)cyclopentadiene

(E)-9-iodo-2,6-dimethylnona-2,6-diene

(2S-trans)-2,5-Dimethyl-1-<1-oxo-5-(phenylmethoxy)-pentyl>pyrrolidine

5-benzyloxypentanoic acid

Downstream raw materials:

(-)-Secodaphniphylline

(1R,2S)-2-(4-Benzyloxy-1-formyl-butyl)-1-((E)-4,8-dimethyl-nona-3,7-dienyl)-cyclopentanecarbaldehyde

(-)-17,18-Didehydro-23-(phenylmethoxy)-12,16-cyclo-1,12-secodaphnane

5-Benzyloxy-2-[(1S,2R)-2-((E)-4,8-dimethyl-nona-3,7-dienyl)-2-hydroxymethyl-cyclopentyl]-pentan-1-ol