(R)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-1-(toluene-4-sulfonyl)-aziridine

Base Information

Chemical Name:(R)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-1-(toluene-4-sulfonyl)-aziridine
CAS No.:144076-10-8
Molecular Formula:C₁₉H₂₃NO₃S
Molecular Weight:345.463
Hs Code.:

Synonyms:(R)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-1-(toluene-4-sulfonyl)-aziridine

Suppliers and Price of (R)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-1-(toluene-4-sulfonyl)-aziridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-1-(toluene-4-sulfonyl)-aziridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-1-(toluene-4-sulfonyl)-aziridine

There total 1 articles about (R)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-1-(toluene-4-sulfonyl)-aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 143996-26-3,143996-29-6,144125-94-0
N-((1S,2S)-3-Benzyloxy-1-hydroxymethyl-2-methyl-propyl)-4-methyl-benzenesulfonamide

: 144076-10-8
(R)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-1-(toluene-4-sulfonyl)-aziridine

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; Ambient temperature;
DOI:10.1016/S0040-4020(01)89856-2

Reference yield: 82.0%

: 151-50-8
potassium cyanide

: 144076-10-8
(R)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-1-(toluene-4-sulfonyl)-aziridine

: 144088-12-0
N-((1R,2S)-3-Benzyloxy-1-cyanomethyl-2-methyl-propyl)-4-methyl-benzenesulfonamide

Guidance literature:: In methanol; at 40 ℃;
DOI:10.1016/S0040-4020(01)89856-2

Reference yield:

: 144076-10-8
(R)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-1-(toluene-4-sulfonyl)-aziridine

: 144076-09-5,144125-95-1
(S)-4-((R)-2-Benzyloxy-1-methyl-ethyl)-1-(toluene-4-sulfonyl)-azetidin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / methanol / 40 °C

2: 98 percent / 2M NaOH / Heating

3: 60 percent / 4-pyrrolidinopyridine, dicyclohexylcarbodiimide (DCC) / CH₂Cl₂ / 1 h / Ambient temperature

With sodium hydroxide; 4-pyrrolidin-1-ylpyridine; dicyclohexyl-carbodiimide; In methanol; dichloromethane;
DOI:10.1016/S0040-4020(01)89856-2