2-Furancarboxylic acid, 2-[(2-propen-1-ylaMino)thioxoMethyl]hydrazide

Base Information

• Chemical Name: 2-Furancarboxylic acid, 2-[(2-propen-1-ylaMino)thioxoMethyl]hydrazide
• CAS No.: 15886-24-5
• Molecular Formula: C₉H₁₁N₃O₂S
• Molecular Weight: 225.271
• Mol file: 15886-24-5.mol

Synonyms:4-allyl-1-(2-furoyl)-3-thiosemicarbazide

Chemical Property of 2-Furancarboxylic acid, 2-[(2-propen-1-ylaMino)thioxoMethyl]hydrazide

Chemical Property:

• PKA: 9.27±0.70(Predicted)
• Density: 1.252±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

N-Allyl-2-(furan-2-carbonyl)hydrazinecarbothioamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Furancarboxylic acid, 2-[(2-propen-1-ylaMino)thioxoMethyl]hydrazide

There total 1 articles about 2-Furancarboxylic acid, 2-[(2-propen-1-ylaMino)thioxoMethyl]hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-furoic acid hydrazide (3326-71-4) + N-allyl isothiocyanate (57-06-7,58391-87-0) → 4-allyl-1-(2-furoyl)-3-thiosemicarbazide (15886-24-5)

Guidance literature:

With acetonitrile;

DOI:10.1021/ja01637a054

Reference yield: 86.0%

4-allyl-1-(2-furoyl)-3-thiosemicarbazide (15886-24-5) + 4-chlorobenzoylmethyl bromide (536-38-9) → Furan-2-carboxylic acid [3-allyl-4-(4-chloro-phenyl)-3H-thiazol-(2Z)-ylidene]-hydrazide

Guidance literature:

With sodium acetate; In ethanol; for 2h; Heating;

Reference yield: 72.0%

4-allyl-1-(2-furoyl)-3-thiosemicarbazide (15886-24-5) + 4-Nitrophenacyl bromide (99-81-0) → Furan-2-carboxylic acid [3-allyl-4-(4-nitro-phenyl)-3H-thiazol-(2Z)-ylidene]-hydrazide

Guidance literature:

With sodium acetate; In ethanol; for 2h; Heating;

upstream raw materials:

2-furoic acid hydrazide

N-allyl isothiocyanate

Downstream raw materials:

4-allyl-5-(fur-2-yl)-4H-3-mercapto-1,2,4-triazole

Refernces