Technology Process of C26H26N2O
There total 2 articles about C26H26N2O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tris-(dibenzylideneacetone)dipalladium(0); (S)-4-tert-butyl-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-1,3-oxazol;
In
toluene;
at 70 ℃;
for 15h;
enantioselective reaction;
Inert atmosphere;
DOI:10.1002/anie.201209878
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
1.2: 1 h / -78 °C / Inert atmosphere
2.1: potassium tert-butylate / tetrahydrofuran; tert-butyl alcohol / 0 °C
2.2: 0.17 h
3.1: tris-(dibenzylideneacetone)dipalladium(0); (S)-4-tert-butyl-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-1,3-oxazol / toluene / 15 h / 70 °C / Inert atmosphere
With
tris-(dibenzylideneacetone)dipalladium(0); potassium tert-butylate; (S)-4-tert-butyl-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-1,3-oxazol; lithium diisopropyl amide;
In
tetrahydrofuran; toluene; tert-butyl alcohol;
DOI:10.1002/anie.201209878