benzyl (S)-2-[(1-{[4-methoxy-2-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy]carbonyl}-1-methylethoxy)methyl]pyrrolidine-1-carboxylate

Base Information

Chemical Name:benzyl (S)-2-[(1-{[4-methoxy-2-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy]carbonyl}-1-methylethoxy)methyl]pyrrolidine-1-carboxylate
CAS No.:1140458-84-9
Molecular Formula:C₃₂H₃₃N₃O₇
Molecular Weight:571.63
Hs Code.:

Synonyms:benzyl (S)-2-[(1-{[4-methoxy-2-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy]carbonyl}-1-methylethoxy)methyl]pyrrolidine-1-carboxylate

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Chemical Property of benzyl (S)-2-[(1-{[4-methoxy-2-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy]carbonyl}-1-methylethoxy)methyl]pyrrolidine-1-carboxylate

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Technology Process of benzyl (S)-2-[(1-{[4-methoxy-2-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy]carbonyl}-1-methylethoxy)methyl]pyrrolidine-1-carboxylate

There total 1 articles about benzyl (S)-2-[(1-{[4-methoxy-2-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy]carbonyl}-1-methylethoxy)methyl]pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1140458-83-8
benzyl (S)-2-[(1-carboxy-1-methylethoxy)methyl]pyrrolidine-1-carboxylate

: 161288-64-8
2-(2-hydroxy-5-methoxyphenyl)–3H-quinazolin-4-one

: 1140458-84-9
benzyl (S)-2-[(1-{[4-methoxy-2-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy]carbonyl}-1-methylethoxy)methyl]pyrrolidine-1-carboxylate

Guidance literature:: benzyl (S)-2-[(1-carboxy-1-methylethoxy)methyl]pyrrolidine-1-carboxylate; With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; for 0.0833333h;

2-(2-hydroxy-5-methoxyphenyl)–3H-quinazolin-4-one; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1055/s-0028-1083296

Reference yield: 100.0%

: 1140458-84-9
benzyl (S)-2-[(1-{[4-methoxy-2-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy]carbonyl}-1-methylethoxy)methyl]pyrrolidine-1-carboxylate

: 1140458-72-5
(S)-2-[(1-{[4-methoxy-2-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy]carbonyl}-1-methylethoxy)methyl]pyrrolidinium acetate

Guidance literature:: With 10% Pd on charcoal; hydrogen; acetic acid; In methanol; at 20 ℃; for 1.5h; under 750.075 Torr;
DOI:10.1055/s-0028-1083296

Reference yield:

: 1140458-84-9
benzyl (S)-2-[(1-{[4-methoxy-2-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy]carbonyl}-1-methylethoxy)methyl]pyrrolidine-1-carboxylate

: 1140458-74-7
C₉H₁₅NO₂

: 161288-64-8
2-(2-hydroxy-5-methoxyphenyl)–3H-quinazolin-4-one

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In methanol; at 20 ℃; for 0.333333h; under 750.075 Torr;
DOI:10.1055/s-0028-1083296