4-benzylamino-6,7-difluoroquinazoline

Base Information

Chemical Name:4-benzylamino-6,7-difluoroquinazoline
CAS No.:625080-61-7
Molecular Formula:C₁₅H₁₁F₂N₃
Molecular Weight:271.269
Hs Code.:

Synonyms:4-benzylamino-6,7-difluoroquinazoline

Suppliers and Price of 4-benzylamino-6,7-difluoroquinazoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-benzylamino-6,7-difluoroquinazoline

Chemical Property:

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Technology Process of 4-benzylamino-6,7-difluoroquinazoline

There total 3 articles about 4-benzylamino-6,7-difluoroquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-46-9
benzylamine

: 625080-60-6
4-chloro-6,7-difluoroquinazoline

: 625080-61-7
4-benzylamino-6,7-difluoroquinazoline

Guidance literature:: With triethylamine; In isopropyl alcohol; at 20 ℃; for 8h;
DOI:10.1016/S0968-0896(02)00338-3

Reference yield:

: 205259-37-6
6,7-difluoro-3,4-dihydroquinazolin-4-one

: 625080-61-7
4-benzylamino-6,7-difluoroquinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / dimethylformamide / 2 h / Heating

2: 188 mg / Et₃N / propan-2-ol / 8 h / 20 °C

With thionyl chloride; triethylamine; In N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1016/S0968-0896(02)00338-3

Reference yield:

: 211374-80-0
2-amino-4,5-difluorobenzamide

: 625080-61-7
4-benzylamino-6,7-difluoroquinazoline

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / HCl / 4 h / 20 °C

2: SOCl₂ / dimethylformamide / 2 h / Heating

3: 188 mg / Et₃N / propan-2-ol / 8 h / 20 °C

With hydrogenchloride; thionyl chloride; triethylamine; In N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1016/S0968-0896(02)00338-3