2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane 6-endo-oxide

Base Information

• Chemical Name: 2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane 6-endo-oxide
• CAS No.: 149198-12-9
• Molecular Formula: C₂₁H₂₄OS₂
• Molecular Weight: 356.553
• Mol file: 149198-12-9.mol

Synonyms:2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane 6-endo-oxide

Chemical Property of 2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane 6-endo-oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane 6-endo-oxide

There total 5 articles about 2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane 6-endo-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane (125611-59-8) → 2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane 6-exo-oxide + 2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane 6-endo-oxide (149198-12-9)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 4h; Ambient temperature;

DOI:10.1021/ja00064a072

Reference yield: 26.0%

2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane (125611-59-8) → 2,2,4,4-tetramethyl-1,5-diphenyl-5-thioxo-1-pentanone (139210-00-7) + 2,2,4-Trimethyl-4-((1S,3R)-1-oxo-3-phenyl-1λ4-dithiiran-3-yl)-1-phenyl-pentan-1-one + 2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane 6-endo-oxide (149198-12-9) + 3-phenyl-3-(1,1,3,3-tetramethyl-4-oxo-4-phenylbutyl)dithiirane (155795-05-4)

Guidance literature:

With potassium hydroxide; potassium sulfate; potassium hydrogensulfate; potassium peroxomonosulfate; Me(C₈H₁₇)3NCl; In dichloromethane; at 9 ℃; for 96h; Further byproducts given; pH 7;

DOI:10.1246/bcsj.70.509

Reference yield: 20.0%

2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane (125611-59-8) → 2,2,4,4-tetramethyl-1,5-diphenylpentane-1,5-dione (95581-35-4) + 2,2,4-Trimethyl-4-((1S,3R)-1-oxo-3-phenyl-1λ4-dithiiran-3-yl)-1-phenyl-pentan-1-one + 2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane 6-endo-oxide (149198-12-9) + 3-phenyl-3-(1,1,3,3-tetramethyl-4-oxo-4-phenylbutyl)dithiirane (155795-05-4)

Guidance literature:

With potassium hydroxide; potassium sulfate; potassium hydrogensulfate; potassium peroxomonosulfate; Aliquat 336; In dichloromethane; water; at 0 ℃; for 144h; pH 4 - 5;

upstream raw materials:

2,2,4,4-tetramethyl-1,5-diphenyl-6,7-dithiabicyclo<3.1.1>heptane

Downstream raw materials:

2,2,4,4-tetramethyl-1,5-diphenyl-5-thioxo-1-pentanone

2,2,4,4-tetramethyl-1,5-diphenylpentane-1,5-dione