3-(Hydroxymethyl)sulphur pentafluoride, 3-(Pentafluorosulphanyl)benzyl alcohol

Base Information

• Chemical Name: 3-(Hydroxymethyl)sulphur pentafluoride, 3-(Pentafluorosulphanyl)benzyl alcohol
• CAS No.: 773872-71-2
• Molecular Formula: C₇H₇F₅OS
• Molecular Weight: 234.19
• Hs Code.: 2930909899
• Mol file: 773872-71-2.mol

Synonyms:(3-pentafluorosulfanylphenyl)methanol

Chemical Property of 3-(Hydroxymethyl)sulphur pentafluoride, 3-(Pentafluorosulphanyl)benzyl alcohol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

3-(Pentafluorosulfur)benzylAlcohol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(Hydroxymethyl)sulphur pentafluoride, 3-(Pentafluorosulphanyl)benzyl alcohol

There total 2 articles about 3-(Hydroxymethyl)sulphur pentafluoride, 3-(Pentafluorosulphanyl)benzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

3-(pentafluorosulfanyl)benzaldehyde (401892-80-6) + phenylboronic acid (98-80-6) → (3-pentafluorosulfanylphenyl)methanol (773872-71-2) + [3-(pentafluorosulfanyl)phenyl](phenyl)methanone (1402070-43-2) + (R)-(3-(pentafluorosulfanyl)phenyl)phenylmethanol + (S)-(3-(pentafluorosulfanyl)phenyl)phenylmethanol

Guidance literature:

With [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; potassium carbonate; In water; toluene; at 110 ℃; for 17h; enantioselective reaction; Inert atmosphere;

DOI:10.1039/c6ob01663d

Reference yield:

→ (3-pentafluorosulfanylphenyl)methanol (773872-71-2)

Guidance literature:

Reference yield: 70.0%

(3-pentafluorosulfanylphenyl)methanol (773872-71-2) + 4-chloro-5-(1,3-dioxan-2-yl)pyrimidine → 3-((5-(1,3-dioxan-2-yl)pyrimidin-4-yloxy)methyl)phenylpentafluoro thioether

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 4h;

upstream raw materials:

3-(pentafluorosulfanyl)benzaldehyde

phenylboronic acid