(R)-2,3,5,6-tetrafluoro-4-methylbenzyl 3-(4-methoxyphenyl)-4-(p-tolyl)butanoate

Base Information

Chemical Name:(R)-2,3,5,6-tetrafluoro-4-methylbenzyl 3-(4-methoxyphenyl)-4-(p-tolyl)butanoate
CAS No.:1462941-07-6
Molecular Formula:C₂₆H₂₄F₄O₃
Molecular Weight:460.468
Hs Code.:

Synonyms:(R)-2,3,5,6-tetrafluoro-4-methylbenzyl 3-(4-methoxyphenyl)-4-(p-tolyl)butanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2,3,5,6-tetrafluoro-4-methylbenzyl 3-(4-methoxyphenyl)-4-(p-tolyl)butanoate

Chemical Property:

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Technology Process of (R)-2,3,5,6-tetrafluoro-4-methylbenzyl 3-(4-methoxyphenyl)-4-(p-tolyl)butanoate

There total 2 articles about (R)-2,3,5,6-tetrafluoro-4-methylbenzyl 3-(4-methoxyphenyl)-4-(p-tolyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79538-03-7
2,3,5,6-tetrafluoro-4-methylbenzyl alcohol

: 1610701-00-2
C₁₈H₂₀O₃

: 1462941-07-6
(R)-2,3,5,6-tetrafluoro-4-methylbenzyl 3-(4-methoxyphenyl)-4-(p-tolyl)butanoate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In acetonitrile; at 20 ℃; for 10h;
DOI:10.1016/j.bmcl.2014.04.055

Reference yield:

: 1610700-96-3
C₂₈H₃₅NO₄S

: 1462941-07-6
(R)-2,3,5,6-tetrafluoro-4-methylbenzyl 3-(4-methoxyphenyl)-4-(p-tolyl)butanoate

Guidance literature:: Multi-step reaction with 2 steps

1: lithium hydroxide; dihydrogen peroxide / tetrahydrofuran; water / 12 h / 0 °C

2: dmap; dicyclohexyl-carbodiimide / acetonitrile / 10 h / 20 °C

With dmap; dihydrogen peroxide; dicyclohexyl-carbodiimide; lithium hydroxide; In tetrahydrofuran; water; acetonitrile;
DOI:10.1016/j.bmcl.2014.04.055