C₂HF₃O₂*C₂₇H₂₉N₇O₁₀S₂

Base Information

• Chemical Name: C₂HF₃O₂*C₂₇H₂₉N₇O₁₀S₂
• CAS No.: 1381974-71-5
• Molecular Formula: C₂HF₃O₂*C₂₇H₂₉N₇O₁₀S₂
• Molecular Weight: 789.724
• Mol file: 1381974-71-5.mol

Synonyms:C₂HF₃O₂*C₂₇H₂₉N₇O₁₀S₂

Chemical Property of C₂HF₃O₂*C₂₇H₂₉N₇O₁₀S₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂HF₃O₂*C₂₇H₂₉N₇O₁₀S₂

There total 7 articles about C₂HF₃O₂*C₂₇H₂₉N₇O₁₀S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

C40H45N7O13S2 + trifluoroacetic acid (76-05-1) → C2HF3O2*C27H29N7O10S2 (1381974-71-5)

Guidance literature:

With methyl-phenyl-thioether; In dichloromethane; at 0 ℃; for 6h;

DOI:10.1002/asia.201100647

Reference yield:

C2HF3O2*C10H14N4O5 (1381969-33-0) → C2HF3O2*C27H29N7O10S2 (1381974-71-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 24 h / 0 - 20 °C

2.1: chlorotriisopropylsilane; trifluoroacetic acid / dichloromethane / 2 h

3.1: 4-methyl-morpholine; triethylamine / dichloromethane / 4 h / 0 °C

4.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 1 h / 0 °C

4.2: 42 h / 0 - 20 °C

5.1: methyl-phenyl-thioether / dichloromethane / 6 h / 0 °C

With 4-methyl-morpholine; chlorotriisopropylsilane; methyl-phenyl-thioether; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/asia.201100647

Reference yield:

C15H22N4O7 (1359745-84-8) → C2HF3O2*C27H29N7O10S2 (1381974-71-5)

Guidance literature:

Multi-step reaction with 6 steps

1.1: dichloromethane / 1.5 h

2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 24 h / 0 - 20 °C

3.1: chlorotriisopropylsilane; trifluoroacetic acid / dichloromethane / 2 h

4.1: 4-methyl-morpholine; triethylamine / dichloromethane / 4 h / 0 °C

5.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 1 h / 0 °C

5.2: 42 h / 0 - 20 °C

6.1: methyl-phenyl-thioether / dichloromethane / 6 h / 0 °C

With 4-methyl-morpholine; chlorotriisopropylsilane; methyl-phenyl-thioether; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/asia.201100647

upstream raw materials:

4-((triphenylmethyl)thio)benzoic acid

C₁₅H₂₂N₄O₇

C₂HF₃O₂*C₁₀H₁₄N₄O₅

C₃₆H₃₂N₄O₆S