1,2-Distearoylphosphatidylethanolamine

Base Information

• Chemical Name: 1,2-Distearoylphosphatidylethanolamine
• CAS No.: 4537-76-2
• Molecular Formula: C41H82NO8P
• Molecular Weight: 748.078
• DSSTox Substance ID: DTXSID80865952
• Nikkaji Number: J600.282J
• Mol file: 4537-76-2.mol

Synonyms:1,2-dioctadecanoyl-sn-glycero-3-phosphoethanolamine;1,2-distearoylphosphatidylethanolamine;1,2-distearoylphosphatidylethanolamine, (+-)-isomer;1,2-distearoylphosphatidylethanolamine, (R)-isomer;1,2-distearoylphosphatidylethanolamine, (S)-isomer;DC18PE;distearoyl-L-phosphatidylethanolamine;DSPE

Chemical Property of 1,2-Distearoylphosphatidylethanolamine

Chemical Property:

• PSA: 144.19000
• LogP: 12.75700
• XLogP3: 12.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 43
• Exact Mass: 747.57780557
• Heavy Atom Count: 51
• Complexity: 815

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCN)OC(=O)CCCCCCCCCCCCCCCCC

Technology Process of 1,2-Distearoylphosphatidylethanolamine

There total 27 articles about 1,2-Distearoylphosphatidylethanolamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3-(((allyloxy)(2-(((allyloxy)carbonyl)amino)ethoxy)phosphoryl)oxy)propane-1,2-diyl distearate → distearylphosphatidylethanolamine (4537-76-2)

Guidance literature:

With morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1055/a-1516-9893

Reference yield: 85.0%

C46H90NO10P → distearylphosphatidylethanolamine (4537-76-2)

Guidance literature:

With hydrogenchloride; In dichloromethane; at 20 ℃; for 2h; pH=1; pH-value; Cooling with ice;

Reference yield: 79.0%

C49H88NO10P → distearylphosphatidylethanolamine (4537-76-2)

Guidance literature:

With hydrogenchloride; In dichloromethane; at 20 ℃; for 2h; pH=1; Cooling with ice;

upstream raw materials:

N-(2-Hydroxyethyl)phthalimide

DL-α,β-distearin

phosphoric acid-(2-benzyloxycarbonylamino-ethyl ester)-(2,3-bis-stearoyloxy-propyl ester)-phenyl ester

N-Trityl O-(1,2-disteaoryl-sn-glycero-3-phosphoryl)-ethanolamin

Downstream raw materials:

4-(hydroxymethyl)-2,3,5,6-tetrafluorophenyl azide