Technology Process of 1,2-bis(hydroxymethyl)-3,4,5,6-tetraphenylbenzene
There total 1 articles about 1,2-bis(hydroxymethyl)-3,4,5,6-tetraphenylbenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
aluminum (III) chloride; lithium aluminium tetrahydride;
In
diethyl ether;
at 20 ℃;
for 3h;
Inert atmosphere;
DOI:10.3987/COM-07-S(U)28
- Guidance literature:
-
1,2-bis(hydroxymethyl)-3,4,5,6-tetraphenylbenzene;
With
oxalyl dichloride; dimethyl sulfoxide;
In
dichloromethane;
at -78 ℃;
for 1.16667h;
Inert atmosphere;
With
triethylamine;
In
dichloromethane;
at -78 - 20 ℃;
for 1.5h;
Inert atmosphere;
DOI:10.1016/j.dyepig.2016.09.050
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1.17 h / -78 °C / Inert atmosphere
1.2: 1.5 h / -78 - 20 °C / Inert atmosphere
2.1: TOP / 1,4-dioxane / 4.5 h / Reflux; Inert atmosphere
With
oxalyl dichloride; TOP; dimethyl sulfoxide;
In
1,4-dioxane; dichloromethane;
1.1: |Swern Oxidation / 1.2: |Swern Oxidation;
DOI:10.1016/j.dyepig.2016.09.050
