tert-butyl (E)-3-(3'-methoxyphenyl)prop-2-en-1-yl carbonate

Base Information

• Chemical Name: tert-butyl (E)-3-(3'-methoxyphenyl)prop-2-en-1-yl carbonate
• CAS No.: 1137838-10-8
• Molecular Formula: C₁₅H₂₀O₄
• Molecular Weight: 264.321
• Mol file: 1137838-10-8.mol

Synonyms:tert-butyl (E)-3-(3'-methoxyphenyl)prop-2-en-1-yl carbonate

Chemical Property of tert-butyl (E)-3-(3'-methoxyphenyl)prop-2-en-1-yl carbonate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of tert-butyl (E)-3-(3'-methoxyphenyl)prop-2-en-1-yl carbonate

There total 2 articles about tert-butyl (E)-3-(3'-methoxyphenyl)prop-2-en-1-yl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(E)-3-(3-Methoxyphenyl)-2-propen-1-ol (125617-35-8) + di-tert-butyl dicarbonate (24424-99-5) → tert-butyl (E)-3-(3'-methoxyphenyl)prop-2-en-1-yl carbonate (1137838-10-8)

Guidance literature:

With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide; In dichloromethane; water; at 0 ℃; for 2.5h; Inert atmosphere;

DOI:10.1021/acs.joc.0c01020

Reference yield: 25.0%

3-methoxy-1-iodobenzene (766-85-8) + pinacolyl 1-(tert-butyloxycarbonyl)prop-2-en-1-ol-3-ylboronate → tert-butyl (E)-3-(3'-methoxyphenyl)prop-2-en-1-yl carbonate (1137838-10-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,2-dimethoxyethane; water; at 80 ℃; for 2h; Inert atmosphere;

DOI:10.1135/cccc20080705

Reference yield: 97.0%

tert-butyl (E)-3-(3'-methoxyphenyl)prop-2-en-1-yl carbonate (1137838-10-8) + ethyl 2-diazo-3-hydroxy-3,3-diphenylpropanoate → ethyl (E)-2-benzoyl-5-(3-methoxyphenyl)-2-phenylpent-4-enoate

Guidance literature:

With rhodium(II) pivalate; bis(η3-allyl-μ-chloropalladium(II)); caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; In toluene; at 20 ℃; for 3h; Schlenk technique; Inert atmosphere;

DOI:10.1039/c9cc08559a

upstream raw materials:

3-methoxy-1-iodobenzene

(E)-3-(3-Methoxyphenyl)-2-propen-1-ol

di-tert-butyl dicarbonate

Downstream raw materials:

(R)-ethyl 1-(1-(3-methoxyphenyl)allyl)-1H-indole-2-carboxylate