Technology Process of O-methylulongamide C
There total 19 articles about O-methylulongamide C which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C46H65N5O10S;
With
trifluoroacetic acid;
In
dichloromethane;
for 0.5h;
With
(benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine;
In
N,N-dimethyl-formamide;
at 85 - 90 ℃;
DOI:10.1080/00397911.2011.618284
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 18 h
2.1: trifluoroacetic acid / dichloromethane / 1 h
3.1: dmap; dicyclohexyl-carbodiimide / dichloromethane
4.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 18 h
5.1: triethylamine; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride / dichloromethane / 1 h / 0 - 20 °C
6.1: trifluoroacetic acid / dichloromethane / 0.5 h
6.2: 85 - 90 °C
With
dmap; palladium 10% on activated carbon; hydrogen; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid;
In
dichloromethane; ethyl acetate;
DOI:10.1080/00397911.2011.618284
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: dmap; dicyclohexyl-carbodiimide / dichloromethane
2.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 18 h
3.1: triethylamine; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride / dichloromethane / 1 h / 0 - 20 °C
4.1: trifluoroacetic acid / dichloromethane / 0.5 h
4.2: 85 - 90 °C
With
dmap; palladium 10% on activated carbon; hydrogen; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid;
In
dichloromethane; ethyl acetate;
DOI:10.1080/00397911.2011.618284
