3-Chloro-12,13-dimethoxy-5,9,10,14b-tetrahydroisoquino(2,1-d)(1,4)benz odiazepin-6(7H)-one

Base Information

• Chemical Name: 3-Chloro-12,13-dimethoxy-5,9,10,14b-tetrahydroisoquino(2,1-d)(1,4)benz odiazepin-6(7H)-one
• CAS No.: 82802-88-8
• Molecular Formula: C₁₉H₁₉ClN₂O₃
• Molecular Weight: 358.824
• Mol file: 82802-88-8.mol

Synonyms:

Chemical Property of 3-Chloro-12,13-dimethoxy-5,9,10,14b-tetrahydroisoquino(2,1-d)(1,4)benz odiazepin-6(7H)-one

Chemical Property:

• Vapor Pressure: 1.99E-10mmHg at 25°C
• Boiling Point: 507.7°C at 760 mmHg
• PKA: 13.47±0.20(Predicted)
• Flash Point: 260.8°C
• Density: 1.37g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Chloro-12,13-dimethoxy-5,9,10,14b-tetrahydroisoquino(2,1-d)(1,4)benz odiazepin-6(7H)-one

There total 2 articles about 3-Chloro-12,13-dimethoxy-5,9,10,14b-tetrahydroisoquino(2,1-d)(1,4)benz odiazepin-6(7H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

11-Chloro-2,3-dimethoxy-8-oxo-5,7,8,9-tetrahydro-6H-9-aza-6a-azonia-benzo[6,7]cyclohepta[1,2-a]naphthalene; bromide (54971-40-3) → DL-3-Chlor-12,13-dimethoxy-5,9,10,14b-tetrahydro-7H-isochinolino<2,1-d><1,4>benzodiazepin-6-on (82802-88-8)

Guidance literature:

With hydrogenchloride; In ethanol; at 20 ℃; mercury and calomel electrode;

DOI:10.1002/ardp.19813140604

Reference yield:

→ DL-3-Chlor-12,13-dimethoxy-5,9,10,14b-tetrahydro-7H-isochinolino<2,1-d><1,4>benzodiazepin-6-on (82802-88-8)

Guidance literature:

1-<2-(α-Bromacetylamino)-4-chlor-phenyl>-6,7-dimethoxy-3,4-dihydro-isochinolin-hydrobromid (X), NaBH4;

DOI:10.1007/BF00779359

upstream raw materials:

11-Chloro-2,3-dimethoxy-8-oxo-5,7,8,9-tetrahydro-6H-9-aza-6a-azonia-benzo[6,7]cyclohepta[1,2-a]naphthalene; bromide