ethyl 2-{[4-(allylamino)-2-(benzylsulfanyl)-6-oxo-1,6-dihydro-5-pyrimidinyl]methyl} acrylate

Base Information

Chemical Name:ethyl 2-{[4-(allylamino)-2-(benzylsulfanyl)-6-oxo-1,6-dihydro-5-pyrimidinyl]methyl} acrylate
CAS No.:1308253-12-4
Molecular Formula:C₂₀H₂₃N₃O₃S
Molecular Weight:385.487
Hs Code.:

Synonyms:ethyl 2-{[4-(allylamino)-2-(benzylsulfanyl)-6-oxo-1,6-dihydro-5-pyrimidinyl]methyl} acrylate

Suppliers and Price of ethyl 2-{[4-(allylamino)-2-(benzylsulfanyl)-6-oxo-1,6-dihydro-5-pyrimidinyl]methyl} acrylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of ethyl 2-{[4-(allylamino)-2-(benzylsulfanyl)-6-oxo-1,6-dihydro-5-pyrimidinyl]methyl} acrylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of ethyl 2-{[4-(allylamino)-2-(benzylsulfanyl)-6-oxo-1,6-dihydro-5-pyrimidinyl]methyl} acrylate

There total 1 articles about ethyl 2-{[4-(allylamino)-2-(benzylsulfanyl)-6-oxo-1,6-dihydro-5-pyrimidinyl]methyl} acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 91063-27-3
2-(benzylsulfanyl)-6-chloro-4(3H)-pyrimidinone

: 1308253-12-4
ethyl 2-{[4-(allylamino)-2-(benzylsulfanyl)-6-oxo-1,6-dihydro-5-pyrimidinyl]methyl} acrylate

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / Sealed tube; Heating

2: N,N-dimethyl-formamide / 168 h / 20 °C / Inert atmosphere

In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2011.03.011

Reference yield: 96.0%

: 1308253-12-4
ethyl 2-{[4-(allylamino)-2-(benzylsulfanyl)-6-oxo-1,6-dihydro-5-pyrimidinyl]methyl} acrylate

: 1308253-16-8
8-allyl-2-(benzylsulfanyl)-6-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione

Guidance literature:: With 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; In N,N-dimethyl-formamide; at 100 ℃; for 0.5h; Microwave irradiation;
DOI:10.1016/j.tet.2011.03.011

Reference yield:

: 1308253-12-4
ethyl 2-{[4-(allylamino)-2-(benzylsulfanyl)-6-oxo-1,6-dihydro-5-pyrimidinyl]methyl} acrylate

: 1308253-24-8
8-allyl-2-(benzylamino)-6-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine / N,N-dimethyl-formamide / 0.5 h / 100 °C / Microwave irradiation

2: 3-chloro-benzenecarboperoxoic acid / N,N-dimethyl-formamide / 3 h / 20 °C / Inert atmosphere

3: 1 h / 110 °C / Microwave irradiation

With 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; 3-chloro-benzenecarboperoxoic acid; In N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2011.03.011