Technology Process of C31H35NO3
There total 4 articles about C31H35NO3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-cyclohexylprop-2-en-1-one; C22H21NO2;
With
tin(IV) chloride;
In
dichloromethane;
at -78 ℃;
for 1h;
Inert atmosphere;
Molecular sieve;
diastereoselective reaction;
DOI:10.1021/ol402254p
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran; hexane / 0.75 h / -78 °C / Inert atmosphere
1.2: 2 h / -78 - 20 °C / Inert atmosphere
2.1: CSA / dichloromethane / 0.17 h / 20 °C / Inert atmosphere
3.1: acetonitrile / 16 h / 125 °C / Inert atmosphere; Sealed tube
4.1: tin(IV) chloride / dichloromethane / 1 h / -78 °C / Inert atmosphere; Molecular sieve
With
N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; tin(IV) chloride;
In
tetrahydrofuran; hexane; dichloromethane; acetonitrile;
4.2: |Diels-Alder Cycloaddition;
DOI:10.1021/ol402254p
- Guidance literature:
-
Multi-step reaction with 3 steps
1: CSA / dichloromethane / 0.17 h / 20 °C / Inert atmosphere
2: acetonitrile / 16 h / 125 °C / Inert atmosphere; Sealed tube
3: tin(IV) chloride / dichloromethane / 1 h / -78 °C / Inert atmosphere; Molecular sieve
With
tin(IV) chloride;
In
dichloromethane; acetonitrile;
3: |Diels-Alder Cycloaddition;
DOI:10.1021/ol402254p
