L-Tyrosyl-D-alanyl-glycyl-L-phenylalanyl-L-neopentylglycyl-L-arginine

Base Information

• Chemical Name: L-Tyrosyl-D-alanyl-glycyl-L-phenylalanyl-L-neopentylglycyl-L-arginine
• CAS No.: 126399-19-7
• Molecular Formula: C₃₆H₅₃N₉O₈
• Molecular Weight: 739.872
• Mol file: 126399-19-7.mol

Synonyms:L-Tyrosyl-D-alanyl-glycyl-L-phenylalanyl-L-neopentylglycyl-L-arginine

Chemical Property of L-Tyrosyl-D-alanyl-glycyl-L-phenylalanyl-L-neopentylglycyl-L-arginine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of L-Tyrosyl-D-alanyl-glycyl-L-phenylalanyl-L-neopentylglycyl-L-arginine

There total 5 articles about L-Tyrosyl-D-alanyl-glycyl-L-phenylalanyl-L-neopentylglycyl-L-arginine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-arginine (74-79-3,25212-18-4) → L-Tyrosyl-D-alanyl-glycyl-L-phenylalanyl-L-neopentylglycyl-L-arginine (126399-19-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 88 percent / dimethylformamide / 12 h / Ambient temperature

2: Trifluoro acetic acid / 1) CF₃COOH, 1 h 2) Dowex in OH(-) cycle 3) DMF, 12 h

3: Hydrogen / Pd/C / 1) II hydrogenated in methanol 2) DMF, room temp., 24 h

4: CF₃COOH / 1 h / Ambient temperature

With hydrogen; trifluoroacetic acid; palladium on activated charcoal; In N,N-dimethyl-formamide;

Reference yield:

p-Nitrophenyl ester of tert-butyloxycarbonyl-D,L-neopentylglycine (126399-12-0) → L-Tyrosyl-D-alanyl-glycyl-L-phenylalanyl-L-neopentylglycyl-L-arginine (126399-19-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 88 percent / dimethylformamide / 12 h / Ambient temperature

2: Trifluoro acetic acid / 1) CF₃COOH, 1 h 2) Dowex in OH(-) cycle 3) DMF, 12 h

3: Hydrogen / Pd/C / 1) II hydrogenated in methanol 2) DMF, room temp., 24 h

4: CF₃COOH / 1 h / Ambient temperature

With hydrogen; trifluoroacetic acid; palladium on activated charcoal; In N,N-dimethyl-formamide;

Reference yield:

Tert-butyloxycarbonyl-D,L-neopentylglycyl-L-arginine (126399-14-2,126399-15-3) → L-Tyrosyl-D-alanyl-glycyl-L-phenylalanyl-L-neopentylglycyl-L-arginine (126399-19-7)

Guidance literature:

Multi-step reaction with 3 steps

1: Trifluoro acetic acid / 1) CF₃COOH, 1 h 2) Dowex in OH(-) cycle 3) DMF, 12 h

2: Hydrogen / Pd/C / 1) II hydrogenated in methanol 2) DMF, room temp., 24 h

3: CF₃COOH / 1 h / Ambient temperature

With hydrogen; trifluoroacetic acid; palladium on activated charcoal;

upstream raw materials:

Tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-D-alanyl-glycyl-L-phenylalanyl-D,L-neopentylglycyl-L-arginine

L-arginine

p-Nitrophenyl ester of tert-butyloxycarbonyl-D,L-neopentylglycine

Tert-butyloxycarbonyl-D,L-neopentylglycyl-L-arginine

Downstream raw materials:

L-arginine

Refernces