Technology Process of Tefuryltrione
There total 4 articles about Tefuryltrione which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
methyl 2-chloro-4-(methylsulfonyl)-3-(((tetrahydrofuran-2-yl)methoxy)methyl)benzoate; 1,3-cylohexanedione;
With
ethylenediamine;
In
acetonitrile;
at 20 ℃;
for 1.5h;
With
acetonitrile;
at 20 ℃;
for 2h;
Time;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: thionyl chloride / 3 h / 60 °C
2.1: 2,2'-azobis(isobutyronitrile) / dichloromethane / 3 h / 60 °C
2.2: 7.5 h / 70 °C
3.1: sodium carbonate; zinc(II) sulfate / tetrahydrofuran / 2.5 h / Cooling with ice
4.1: ethylenediamine / acetonitrile / 3 h / 20 °C
With
thionyl chloride; 2,2'-azobis(isobutyronitrile); sodium carbonate; ethylenediamine; zinc(II) sulfate;
In
tetrahydrofuran; dichloromethane; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 2,2'-azobis(isobutyronitrile) / dichloromethane / 3 h / 60 °C
1.2: 7.5 h / 70 °C
2.1: sodium carbonate; zinc(II) sulfate / tetrahydrofuran / 2.5 h / Cooling with ice
3.1: ethylenediamine / acetonitrile / 3 h / 20 °C
With
2,2'-azobis(isobutyronitrile); sodium carbonate; ethylenediamine; zinc(II) sulfate;
In
tetrahydrofuran; dichloromethane; acetonitrile;
