8-fluoro-1-(2-fluoro-4-iodophenyl)-5-methylbenzimidazolo[6,5-d][c]isoxazole

Base Information

Chemical Name:8-fluoro-1-(2-fluoro-4-iodophenyl)-5-methylbenzimidazolo[6,5-d][c]isoxazole
CAS No.:1040246-68-1
Molecular Formula:C₁₅H₈F₂IN₃O₂
Molecular Weight:427.149
Hs Code.:

Synonyms:8-fluoro-1-(2-fluoro-4-iodophenyl)-5-methylbenzimidazolo[6,5-d][c]isoxazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 8-fluoro-1-(2-fluoro-4-iodophenyl)-5-methylbenzimidazolo[6,5-d][c]isoxazole

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Technology Process of 8-fluoro-1-(2-fluoro-4-iodophenyl)-5-methylbenzimidazolo[6,5-d][c]isoxazole

There total 1 articles about 8-fluoro-1-(2-fluoro-4-iodophenyl)-5-methylbenzimidazolo[6,5-d][c]isoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 1040246-67-0
7-fluoro-6-(2-fluoro-4-iodophenylamino)-3-methylbenzo[c]isoxazole-5-carboxylic acid

: 1040246-68-1
8-fluoro-1-(2-fluoro-4-iodophenyl)-5-methylbenzimidazolo[6,5-d][c]isoxazole

Guidance literature:: With diphenyl phosphoryl azide; triethylamine; In toluene; for 4h; Heating / reflux;

Reference yield: 79.0%

: 1040246-68-1
8-fluoro-1-(2-fluoro-4-iodophenyl)-5-methylbenzimidazolo[6,5-d][c]isoxazole

: 139631-62-2
cyclopropanesulfonyl chloride

: 1040246-69-2
3-(cyclopropanesulfonyl)-8-fluoro-1-(2-fluoro-4-iodophenyl)-5-methylbenzimidazolo[6,5-d][c]isoxazole

Guidance literature:: 8-fluoro-1-(2-fluoro-4-iodophenyl)-5-methylbenzimidazolo[6,5-d][c]isoxazole; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.166667h;

cyclopropanesulfonyl chloride; In tetrahydrofuran; at 20 ℃; for 16h;