(S)-N²-9-fluorenylmethoxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-phenylcarbamoyl-4-azalysine

Base Information

• Chemical Name: (S)-N²-9-fluorenylmethoxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-phenylcarbamoyl-4-azalysine
• CAS No.: 439864-53-6
• Molecular Formula: C₃₂H₃₆N₄O₇
• Molecular Weight: 588.66

Synonyms:(S)-N²-9-fluorenylmethoxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-phenylcarbamoyl-4-azalysine

Chemical Property of (S)-N²-9-fluorenylmethoxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-phenylcarbamoyl-4-azalysine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-N²-9-fluorenylmethoxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-phenylcarbamoyl-4-azalysine

There total 10 articles about (S)-N²-9-fluorenylmethoxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-phenylcarbamoyl-4-azalysine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(S)-N6-tert-butoxycarbonyl-N4-phenylcarbamoyl-4-azalysine (439864-48-9) → (S)-N2-9-fluorenylmethoxycarbonyl-N6-tert-butoxycarbonyl-N4-phenylcarbamoyl-4-azalysine (439864-53-6)

Guidance literature:

With sodium hydrogencarbonate; In 1,4-dioxane; water; at 20 ℃; for 5h;

DOI:10.1021/jo010456e

Reference yield:

N-(t-butoxycarbonyl)glycinal (89711-08-0) → (S)-N2-9-fluorenylmethoxycarbonyl-N6-tert-butoxycarbonyl-N4-phenylcarbamoyl-4-azalysine (439864-53-6)

Guidance literature:

Multi-step reaction with 5 steps

1: 65 percent / acetic acid; sodium cyanoborohydride / methanol

2: 69 percent / diethyl ether / 5 h / 20 °C

3: 98 percent / LiOH / H₂O; methanol / 20 °C

4: 78 percent / H₂ / Pd/C / methanol / 20 °C

5: 88 percent / NaHCO₃ / H₂O; dioxane / 5 h / 20 °C

With lithium hydroxide; hydrogen; sodium cyanoborohydride; sodium hydrogencarbonate; acetic acid; palladium on activated charcoal; In 1,4-dioxane; methanol; diethyl ether; water;

DOI:10.1021/jo010456e

Reference yield:

methyl (S)-N2-benzyloxycarbonyl-N6-tert-butoxycarbonyl-N4-phenylcarbamoyl-4-azalysinate (439864-36-5) → (S)-N2-9-fluorenylmethoxycarbonyl-N6-tert-butoxycarbonyl-N4-phenylcarbamoyl-4-azalysine (439864-53-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 98 percent / LiOH / H₂O; methanol / 20 °C

2: 78 percent / H₂ / Pd/C / methanol / 20 °C

3: 88 percent / NaHCO₃ / H₂O; dioxane / 5 h / 20 °C

With lithium hydroxide; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In 1,4-dioxane; methanol; water;

DOI:10.1021/jo010456e

upstream raw materials:

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

(S)-N⁶-tert-butoxycarbonyl-N⁴-phenylcarbamoyl-4-azalysine

di-tert-butyl dicarbonate

2-(N-tert-butoxycarbonylamino)ethanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 439864-53-6 (S)-N²-9-fluorenylmethoxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-phenylcarbamoyl-4-azalysine

Send

Send

Metric Ton KG G Pound L ML

Send

Send