N-(4-(4-Morpholinylsulphonyl)phenyl)acetamide

Base Information

• Chemical Name: N-(4-(4-Morpholinylsulphonyl)phenyl)acetamide
• CAS No.: 21626-69-7
• Molecular Formula: C12H16 N2 O4 S
• Molecular Weight: 284.336
• Hs Code.: 2935009090
• European Community (EC) Number: 244-483-8
• UNII: RBL5FSA93L
• DSSTox Substance ID: DTXSID20176014
• Nikkaji Number: J226.243F
• Wikidata: Q83046350
• ChEMBL ID: CHEMBL1077150
• Mol file: 21626-69-7.mol

Synonyms:21626-69-7;N-(4-(Morpholinosulfonyl)phenyl)acetamide;N-(4-(4-Morpholinylsulphonyl)phenyl)acetamide;N-(4-morpholin-4-ylsulfonylphenyl)acetamide;N-[4-(4-morpholinylsulfonyl)phenyl]acetamide;N-[4-(morpholin-4-ylsulfonyl)phenyl]acetamide;N-[4-(Morpholine-4-sulfonyl)-phenyl]-acetamide;n-[4-(morpholine-4-sulfonyl)phenyl]acetamide;LASSBio-1296;RBL5FSA93L;Oprea1_475247;Oprea1_638545;MLS000035495;SCHEMBL4075002;CHEMBL1077150;DTXSID20176014;HMS2401N18;4'-(Morpholinylsulfonyl)acetanilide;EINECS 244-483-8;MFCD00585314;STK030743;AKOS000485152;Acetanilide, 4'-(morpholinosulfonyl)-;4'-[(4-Morpholinyl)sulfonyl]acetanilide;NCGC00245195-01;SMR000123092;CS-0318301;N-[4-Morpholine-4-sulfonyl)phenyl]acetamide;4'-[(4-Morpholinyl)sulfonyl]acetanilide, 97%;AB00000032-01;Acetamide, N-[4-(4-morpholinylsulfonyl)phenyl]-;AE-641/00396051;SR-01000407295;SR-01000407295-1

Chemical Property of N-(4-(4-Morpholinylsulphonyl)phenyl)acetamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 87.58000
• Density: 1.361g/cm³
• LogP: 2.33410
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 284.08307817
• Heavy Atom Count: 19
• Complexity: 404

Purity/Quality:

99% ^*data from raw suppliers

N-(4-(Morpholinosulfonyl)phenyl)acetamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=CC=C(C=C1)S(=O)(=O)N2CCOCC2

Technology Process of N-(4-(4-Morpholinylsulphonyl)phenyl)acetamide

There total 5 articles about N-(4-(4-Morpholinylsulphonyl)phenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

morpholine (110-91-8,99108-56-2) + p-acetylaminobenzenesulfonyl chloride (121-60-8) → N4-acetylsulfanilylmorpholidate (21626-69-7)

Guidance literature:

With triethylamine; In acetone; at 20 ℃; for 1h;

DOI:10.1007/BF02464305

Reference yield: 70.0%

N-(4-(morpholinodiazenyl)phenyl)acetamide (1939-89-5) → N4-acetylsulfanilylmorpholidate (21626-69-7)

Guidance literature:

With sulfur dioxide; copper dichloride; In acetonitrile; at 70 ℃; for 18h; Inert atmosphere; Schlenk technique;

DOI:10.1039/c4cc03481c

Reference yield: 67.3%

→ N4-acetylsulfanilylmorpholidate (21626-69-7)

Guidance literature:

upstream raw materials:

morpholine

p-acetylaminobenzenesulfonyl chloride

N-acetyl-p-phenylenediamine

N-(4-(morpholinodiazenyl)phenyl)acetamide

Downstream raw materials:

4-(morpholinosulfonyl)aniline

N-{4-[4-(Morpholine-4-sulfonyl)-phenylsulfamoyl]-phenyl}-acetamide