2-pentafluoroethylaniline

Base Information

• Chemical Name: 2-pentafluoroethylaniline
• CAS No.: 60979-05-7
• Molecular Formula: C₈H₆F₅N
• Molecular Weight: 211.134
• Mol file: 60979-05-7.mol

Synonyms:2-pentafluoroethylaniline

Chemical Property of 2-pentafluoroethylaniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-pentafluoroethylaniline

There total 4 articles about 2-pentafluoroethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

Pentafluoroethyl iodide (354-64-3) + 2-iodophenylamine (615-43-0) → 2-pentafluoroethylaniline (60979-05-7)

Guidance literature:

With copper; In N,N-dimethyl-formamide;

DOI:10.1021/jo001001c

Reference yield: 21.0%

Pentafluoroethyl iodide (354-64-3) + aniline (62-53-3) → 4-(1,1,2,2,2-pentafluoroethyl)-phenylamine (60979-04-6) + 2-pentafluoroethylaniline (60979-05-7) + 2,4-bis(pentafluoroethyl)aniline (123068-27-9) + 2,6-bis(pentafluoroethyl)aniline (123068-26-8)

Guidance literature:

With disodium hydrogenphosphate; sodium dithionite; In N,N-dimethyl-formamide; at 65 ℃; for 2h; under 750.06 Torr; also with Na₂S₂O₅, SO₂, Zn;

Reference yield: 14.0%

→ 2-pentafluoroethylaniline (60979-05-7)

Guidance literature:

upstream raw materials:

Pentafluoroethyl iodide

1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane

aniline

2-iodophenylamine

Downstream raw materials:

2-amino-4-(trifluoromethyl)quinoline

9-(trifluoromethyl)acridine