C₂₁H₂₂FN₃O

Base Information

Chemical Name:C₂₁H₂₂FN₃O
CAS No.:1562370-36-8
Molecular Formula:C₂₁H₂₂FN₃O
Molecular Weight:351.424
Hs Code.:

C<sub>21</sub>H<sub>22</sub>FN<sub>3</sub>O

Synonyms:C₂₁H₂₂FN₃O

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₁H₂₂FN₃O

Chemical Property:

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Technology Process of C₂₁H₂₂FN₃O

There total 6 articles about C₂₁H₂₂FN₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N-[7-(bromomethyl)quinolin-2-yl]acetamide

: 104774-86-9
3-(3-fluorophenyl)-propan-1-amine

: 1562370-36-8
C₂₁H₂₂FN₃O

Guidance literature:: 3-(3-fluorophenyl)-propan-1-amine; With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

N-[7-(bromomethyl)quinolin-2-yl]acetamide; With hydrogenchloride; In N,N-dimethyl-formamide; at 20 ℃; for 16h;
DOI:10.1021/jm401838x

Reference yield:

: 57830-64-5,769968-22-1
3′-methylcinnamanilide

: 1562370-36-8
C₂₁H₂₂FN₃O

Guidance literature:: Multi-step reaction with 4 steps

1.1: aluminum (III) chloride / chlorobenzene / 2 h / 90 °C

1.2: 1.17 h / Reflux

2.1: potassium carbonate / chlorobenzene / 17 h / 230 °C

3.1: N-Bromosuccinimide; dibenzoyl peroxide / benzene / 4 h / Inert atmosphere; Reflux

4.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C

4.2: 16 h / 20 °C

With aluminum (III) chloride; N-Bromosuccinimide; potassium carbonate; caesium carbonate; dibenzoyl peroxide; In N,N-dimethyl-formamide; chlorobenzene; benzene;
DOI:10.1021/jm401838x

Reference yield:

: N-(7-methylquinolin-2-yl)acetamide

: 1562370-36-8
C₂₁H₂₂FN₃O

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-Bromosuccinimide; dibenzoyl peroxide / benzene / 4 h / Inert atmosphere; Reflux

2.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C

2.2: 16 h / 20 °C

With N-Bromosuccinimide; caesium carbonate; dibenzoyl peroxide; In N,N-dimethyl-formamide; benzene;
DOI:10.1021/jm401838x