(4R,4'R,5S,5'S)-2,2'-(propane-2,2-diyl)bis(4-(4-bromophenyl)-5-(methoxymethyl)-4,5-dihydrooxazole)

Base Information

Chemical Name:(4R,4'R,5S,5'S)-2,2'-(propane-2,2-diyl)bis(4-(4-bromophenyl)-5-(methoxymethyl)-4,5-dihydrooxazole)
CAS No.:1192597-59-3
Molecular Formula:C₂₅H₂₈Br₂N₂O₄
Molecular Weight:580.316
Hs Code.:

Synonyms:(4R,4'R,5S,5'S)-2,2'-(propane-2,2-diyl)bis(4-(4-bromophenyl)-5-(methoxymethyl)-4,5-dihydrooxazole)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4R,4'R,5S,5'S)-2,2'-(propane-2,2-diyl)bis(4-(4-bromophenyl)-5-(methoxymethyl)-4,5-dihydrooxazole)

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Technology Process of (4R,4'R,5S,5'S)-2,2'-(propane-2,2-diyl)bis(4-(4-bromophenyl)-5-(methoxymethyl)-4,5-dihydrooxazole)

There total 1 articles about (4R,4'R,5S,5'S)-2,2'-(propane-2,2-diyl)bis(4-(4-bromophenyl)-5-(methoxymethyl)-4,5-dihydrooxazole) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₅H₃₂Br₂N₂O₆

: 1192597-59-3
(4R,4'R,5S,5'S)-2,2'-(propane-2,2-diyl)bis(4-(4-bromophenyl)-5-(methoxymethyl)-4,5-dihydrooxazole)

Guidance literature:: With diethylamino-sulfur trifluoride; In dichloromethane; at -78 - 20 ℃;
DOI:10.1016/j.tet.2009.07.053

Reference yield: 94.0%

: 1192597-59-3
(4R,4'R,5S,5'S)-2,2'-(propane-2,2-diyl)bis(4-(4-bromophenyl)-5-(methoxymethyl)-4,5-dihydrooxazole)

: 23112-96-1
(2,6-dimethoxyphenyl)boronic acid

: 1192597-67-3
C₄₁H₄₆N₂O₈

Guidance literature:: With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; [Pd₂(dba)₃]*benzene; caesium carbonate; In toluene; at 100 ℃; for 16h; Inert atmosphere;
DOI:10.1016/j.tet.2009.07.053

Reference yield: 77.0%

: 1192597-59-3
(4R,4'R,5S,5'S)-2,2'-(propane-2,2-diyl)bis(4-(4-bromophenyl)-5-(methoxymethyl)-4,5-dihydrooxazole)

: 98-80-6
phenylboronic acid

: 1192597-60-6
C₃₇H₃₈N₂O₄

Guidance literature:: With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; [Pd₂(dba)₃]*benzene; caesium carbonate; In toluene; at 100 ℃; for 16h; Inert atmosphere;
DOI:10.1016/j.tet.2009.07.053