(E)-methyl 5-(2-methyl-1,3-dioxolan-2-yl)pent-2-enoate

Base Information

Chemical Name:(E)-methyl 5-(2-methyl-1,3-dioxolan-2-yl)pent-2-enoate
CAS No.:1386999-48-9
Molecular Formula:C₁₀H₁₆O₄
Molecular Weight:200.235
Hs Code.:

Synonyms:(E)-methyl 5-(2-methyl-1,3-dioxolan-2-yl)pent-2-enoate

Suppliers and Price of (E)-methyl 5-(2-methyl-1,3-dioxolan-2-yl)pent-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-methyl 5-(2-methyl-1,3-dioxolan-2-yl)pent-2-enoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-methyl 5-(2-methyl-1,3-dioxolan-2-yl)pent-2-enoate

There total 1 articles about (E)-methyl 5-(2-methyl-1,3-dioxolan-2-yl)pent-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 29021-98-5
3-(2-methyl-[1,3]dioxolan-2-yl)-propan-1-ol

: 1386999-48-9
(E)-methyl 5-(2-methyl-1,3-dioxolan-2-yl)pent-2-enoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 °C / Inert atmosphere

1.2: 1.25 h / -78 - 20 °C / Inert atmosphere

2.1: dichloromethane / 17 h / 20 °C

With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; 2.1: Wittig reaction;
DOI:10.1002/adsc.201100917

Reference yield:

: 1386999-48-9
(E)-methyl 5-(2-methyl-1,3-dioxolan-2-yl)pent-2-enoate

: 1243634-58-3
(-)-methyl (1R,2R,3S,5S)-3-(benzoyloxy)-1,8-dimethyl-8-azabicyclo[3.2.1]octane-2-carboxylate

Guidance literature:: Multi-step reaction with 10 steps

1: diisobutylaluminium hydride / hexane; dichloromethane / 2 h / -78 °C / Inert atmosphere

2: manganese(IV) oxide / dichloromethane / 24 h

3: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine / chloroform / 41 h / 4 °C

4: chloroform / 2 h / 20 °C

5: triethylsilane; triethylamine; palladium dichloride / dichloromethane / 8 h / Inert atmosphere; Reflux

6: hydrogenchloride; water / tetrahydrofuran / 2 h / 20 °C

7: aluminum tri-tert-butoxide / toluene / 68 h / 20 - 150 °C / pressure tube

8: benzene / 24 h / 85 °C

9: palladium 10% on activated carbon; hydrogen / methanol / 24 h / 20 °C / 2585.81 - 3620.13 Torr

10: dmap; triethylamine / dichloromethane / 17 h / 0 - 20 °C

With hydrogenchloride; triethylsilane; dmap; manganese(IV) oxide; (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; palladium 10% on activated carbon; water; hydrogen; diisobutylaluminium hydride; aluminum tri-tert-butoxide; triethylamine; palladium dichloride; In tetrahydrofuran; methanol; hexane; dichloromethane; chloroform; toluene; benzene; 3: Michael condensation / 4: Wittig reaction / 8: sealed pressure tube;
DOI:10.1002/adsc.201100917

Reference yield:

: 1386999-48-9
(E)-methyl 5-(2-methyl-1,3-dioxolan-2-yl)pent-2-enoate

: C₂₃H₃₇NO₆Si

Guidance literature:: Multi-step reaction with 3 steps

1: diisobutylaluminium hydride / hexane; dichloromethane / 2 h / -78 °C / Inert atmosphere

2: manganese(IV) oxide / dichloromethane / 24 h

3: (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine / chloroform / 41 h / 4 °C

With manganese(IV) oxide; (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine; diisobutylaluminium hydride; In hexane; dichloromethane; chloroform; 3: Michael condensation;
DOI:10.1002/adsc.201100917