2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9-purinyl]-4-hydroxy-2-(hydroxymethyl)-3-oxolanyl]-3-(4-methoxyphenyl)propanamide

Base Information

• Chemical Name: 2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9-purinyl]-4-hydroxy-2-(hydroxymethyl)-3-oxolanyl]-3-(4-methoxyphenyl)propanamide
• CAS No.: 5682-30-4
• Molecular Formula: C₂₂H₂₉N₇O₅
• Molecular Weight: 471.516
• DSSTox Substance ID: DTXSID801127465
• Nikkaji Number: J831.326A
• Wikidata: Q27165569

Synonyms:2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9-purinyl]-4-hydroxy-2-(hydroxymethyl)-3-oxolanyl]-3-(4-methoxyphenyl)propanamide;BSPBio_001062;SCHEMBL3042415;CHEBI:93834;DTXSID801127465;HMS1792F03;HMS1990F03;AKOS015969738;NCGC00163476-02;2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide;5682-30-4;BRD-A26222320-001-02-6;Q27165569;3'-Deoxy-3'-[3-(4-methoxyphenyl)-2-aminopropanoylamino]-N,N-dimethyladenosine;Adenosine, 3'-[[2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-

Chemical Property of 2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9-purinyl]-4-hydroxy-2-(hydroxymethyl)-3-oxolanyl]-3-(4-methoxyphenyl)propanamide

Chemical Property:

• XLogP3: 0
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 8
• Exact Mass: 471.22301705
• Heavy Atom Count: 34
• Complexity: 680

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O
• Isomeric SMILES: CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O

Technology Process of 2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9-purinyl]-4-hydroxy-2-(hydroxymethyl)-3-oxolanyl]-3-(4-methoxyphenyl)propanamide

There total 2 articles about 2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9-purinyl]-4-hydroxy-2-(hydroxymethyl)-3-oxolanyl]-3-(4-methoxyphenyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Puromycin dihydrochloride (58-58-2,3506-23-8) → puromycin (5682-30-4)

Guidance literature:

With pyridine;

DOI:10.1055/s-1983-30368

Reference yield:

→ puromycin (5682-30-4)

Guidance literature:

aus O-Dimethylpuromycin, Tyr-O-methylierung durch Streptomyces alboniger;

Reference yield: 70.0%

puromycin (5682-30-4) + O3'-(4,5-dimethyl-2-oxo-2λ5-[1,3,2]dioxaphosphol-2-yl)-O5'-(4-methoxy-trityl)-thymidine (62930-00-1) → C56H64N9O14P (86988-25-2)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; 1.) 0 degC, 10h, 2.) 20 degC, 2h;

DOI:10.1055/s-1983-30368

upstream raw materials:

Puromycin dihydrochloride

Downstream raw materials:

C₅₆H₆₄N₉O₁₄P

Thymidylyl(3'->5')puromycin triethylammonium salt

Thymidylyl(3'->5')puromycin

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 5682-30-4 puromycin

Send

Send

Metric Ton KG G Pound L ML

Send

Send