(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)benzo[d]thiazol-6-yl)acetic acid

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Chemical Name:(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)benzo[d]thiazol-6-yl)acetic acid
CAS No.:1471250-02-8
Molecular Formula:C₂₇H₂₅ClN₄O₃S
Molecular Weight:521.039
Hs Code.:

Synonyms:(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)benzo[d]thiazol-6-yl)acetic acid

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Chemical Property of (S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)benzo[d]thiazol-6-yl)acetic acid

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Technology Process of (S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)benzo[d]thiazol-6-yl)acetic acid

There total 15 articles about (S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)benzo[d]thiazol-6-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1471256-63-9
(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)benzo[d]thiazol-6-yl)ethanol

: 1471250-02-8
(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)benzo[d]thiazol-6-yl)acetic acid

Guidance literature:: With chromium(VI) oxide; periodic acid; In water; acetonitrile; at 20 ℃; for 1h;

Reference yield:

: 1150617-54-1
6-bromo-1H-pyrazolo[4,3-b]pyridine

: 1471250-02-8
(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)benzo[d]thiazol-6-yl)acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: caesium carbonate / N,N-dimethyl-formamide / 0.08 h / 20 °C

1.2: 2 h

2.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / dichloromethane; 1,4-dioxane / 2 h / 100 °C

2.2: 1 h / 90 °C

3.1: water; sodium hydroxide / tetrahydrofuran; methanol / 2 h / 45 °C

4.1: periodic acid; chromium(VI) oxide / acetonitrile; water / 1 h / 20 °C

With chromium(VI) oxide; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; water; potassium acetate; caesium carbonate; periodic acid; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 1471256-62-8
(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-1H-pyrazolo[4,3-b]pyridine-6-yl)benzo[d]thiazol-6-yl)ethyl pivalate

: 1471250-02-8
(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-1H-pyrazolo[4,3-b]pyridin-6-yl)benzo[d]thiazol-6-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: water; sodium hydroxide / tetrahydrofuran; methanol / 2 h / 45 °C

2: periodic acid; chromium(VI) oxide / acetonitrile; water / 1 h / 20 °C

With chromium(VI) oxide; water; periodic acid; sodium hydroxide; In tetrahydrofuran; methanol; water; acetonitrile;