Technology Process of 4β-(2'-1',3'-dithiolan)-3α,4α,5α-trimethyl-cyclohexanone
There total 5 articles about 4β-(2'-1',3'-dithiolan)-3α,4α,5α-trimethyl-cyclohexanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(I) bromide dimethylsulfide complex;
In
diethyl ether;
for 4h;
from -78 deg C to -30 deg C;
DOI:10.1016/S0040-4020(01)88114-X
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) hydroquinone; 2.) 2N HCl / 1.) 140 deg C, 14-18 h.; 2.) THF, 30 min.
2: 66 percent / p-TSA / benzene / Heating
3: 67 percent / thallium (III) nitrate trihydrate / tetrahydrofuran; methanol / 0.08 h / 0 °C
4: 82 percent / cuprous bromide-dimethyl sulphide complex / diethyl ether / 4 h / from -78 deg C to -30 deg C
With
hydrogenchloride; copper(I) bromide dimethylsulfide complex; hydroquinone; thallium(III) nitrate;
toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; diethyl ether; benzene;
DOI:10.1016/S0040-4020(01)88114-X
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 66 percent / p-TSA / benzene / Heating
2: 67 percent / thallium (III) nitrate trihydrate / tetrahydrofuran; methanol / 0.08 h / 0 °C
3: 82 percent / cuprous bromide-dimethyl sulphide complex / diethyl ether / 4 h / from -78 deg C to -30 deg C
With
copper(I) bromide dimethylsulfide complex; thallium(III) nitrate;
toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; diethyl ether; benzene;
DOI:10.1016/S0040-4020(01)88114-X
