L-Phenylalanine, N-((4E)-5-(2-furanyl)-3-oxo-4-pentenyl)-, methyl ester

Base Information

Chemical Name:L-Phenylalanine, N-((4E)-5-(2-furanyl)-3-oxo-4-pentenyl)-, methyl ester
CAS No.:159086-02-9
Molecular Formula:C₁₉H₂₁NO₄
Molecular Weight:327.38
Hs Code.:
Wikidata:Q76389559
Mol file:159086-02-9.mol

Synonyms:L-Phenylalanine, N-((4E)-5-(2-furanyl)-3-oxo-4-pentenyl)-, methyl ester;N-((4E)-5-(2-Furanyl)-3-oxo-4-pentenyl)-L-phenylalanine methyl ester;L-Phenylalanine, N-(5-(2-furanyl)-3-oxo-4-pentenyl)-, methyl ester, (E)-;159086-02-9;LS-105789

Suppliers and Price of L-Phenylalanine, N-((4E)-5-(2-furanyl)-3-oxo-4-pentenyl)-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of L-Phenylalanine, N-((4E)-5-(2-furanyl)-3-oxo-4-pentenyl)-, methyl ester

Chemical Property:

Vapor Pressure:1.02E-09mmHg at 25°C
Boiling Point:489.2°C at 760 mmHg
Flash Point:249.7°C
Density:1.157g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:327.14705815
Heavy Atom Count:24
Complexity:429

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C(CC1=CC=CC=C1)NCCC(=O)C=CC2=CC=CO2
Isomeric SMILES:COC(=O)[C@H](CC1=CC=CC=C1)NCCC(=O)/C=C/C2=CC=CO2

Technology Process of L-Phenylalanine, N-((4E)-5-(2-furanyl)-3-oxo-4-pentenyl)-, methyl ester

There total 2 articles about L-Phenylalanine, N-((4E)-5-(2-furanyl)-3-oxo-4-pentenyl)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.1%

: 73400-26-7
1-(2-furfuryl)-3-trimethylsilyloxy-1,3-butadiene

: methyl (S)-2-(methylideneamino)-3-phenylpropanoate

: 159086-02-9
(S)-2-((E)-5-Furan-2-yl-3-oxo-pent-4-enylamino)-3-phenyl-propionic acid methyl ester

Guidance literature:: tin(IV) chloride; In tetrahydrofuran; at -15 - 0 ℃;
DOI:10.1007/BF02464191

Reference yield:

: 7524-50-7
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

: 159086-02-9
(S)-2-((E)-5-Furan-2-yl-3-oxo-pent-4-enylamino)-3-phenyl-propionic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether; H₂O / 0.5 h

2: 93.1 percent / SnCl₄ / tetrahydrofuran / -15 - 0 °C

tin(IV) chloride; In tetrahydrofuran; diethyl ether; water; 1: Condensation / 2: Addition;
DOI:10.1007/BF02464191