1,4-Bis(2-cyan-3-methyl-2-trimethylsiloxy-but-3-enyl)-benzol

Base Information

• Chemical Name: 1,4-Bis(2-cyan-3-methyl-2-trimethylsiloxy-but-3-enyl)-benzol
• CAS No.: 154147-71-4
• Molecular Formula: C₂₄H₃₆N₂O₂Si₂
• Molecular Weight: 440.733
• Mol file: 154147-71-4.mol

Synonyms:1,4-Bis(2-cyan-3-methyl-2-trimethylsiloxy-but-3-enyl)-benzol

Chemical Property of 1,4-Bis(2-cyan-3-methyl-2-trimethylsiloxy-but-3-enyl)-benzol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-Bis(2-cyan-3-methyl-2-trimethylsiloxy-but-3-enyl)-benzol

There total 1 articles about 1,4-Bis(2-cyan-3-methyl-2-trimethylsiloxy-but-3-enyl)-benzol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-bis(bromomethyl)benzene (623-24-5) + 2-<(trimethylsilyl)oxy>-3-methyl-3-butenenitrile (60550-34-7) → 1,4-Bis(2-cyan-3-methyl-2-trimethylsiloxy-but-3-enyl)-benzol (154147-71-4)

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, from -78 deg C to -60 deg C, 1 h, 2.) THF, RT, 8 h;

DOI:10.1002/prac.19943360108

Reference yield: 81.0%

1,4-Bis(2-cyan-3-methyl-2-trimethylsiloxy-but-3-enyl)-benzol (154147-71-4) → 1,4-Bis(3-methyl-2-oxo-but-3-enyl)-benzol (154147-72-5)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In tetrahydrofuran; for 12h; Ambient temperature;

DOI:10.1002/prac.19943360108

Reference yield:

1,4-Bis(2-cyan-3-methyl-2-trimethylsiloxy-but-3-enyl)-benzol (154147-71-4) → 1,4-Bis(3-methyl-2-oxo-4-piperidino-butyl)-benzol (154147-73-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / NEt₃*3HF / tetrahydrofuran / 12 h / Ambient temperature

2: 75 percent / 0.5 h / 100 °C

With triethylamine tris(hydrogen fluoride); In tetrahydrofuran;

DOI:10.1002/prac.19943360108

upstream raw materials:

1,4-bis(bromomethyl)benzene

2-<(trimethylsilyl)oxy>-3-methyl-3-butenenitrile

Downstream raw materials:

1,4-Bis(3-methyl-2-oxo-but-3-enyl)-benzol

1,4-Bis(3-methyl-2-oxo-4-piperidino-butyl)-benzol

1,4-Bis<2-hydroxy-3-methyl-4-piperidino-2-(pyrid-2-yl)-butyl>-benzol