Phenylsulfamoyl-acetic acid tert-butyl ester

Base Information

• Chemical Name: Phenylsulfamoyl-acetic acid tert-butyl ester
• CAS No.: 82185-45-3
• Molecular Formula: C₁₂H₁₇NO₄S
• Molecular Weight: 271.337
• Mol file: 82185-45-3.mol

Synonyms:Phenylsulfamoyl-acetic acid tert-butyl ester

Chemical Property of Phenylsulfamoyl-acetic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phenylsulfamoyl-acetic acid tert-butyl ester

There total 3 articles about Phenylsulfamoyl-acetic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

t-butyl N-phenyl sulfinamoyl acetate (82185-52-2) → Phenylsulfamoyl-acetic acid tert-butyl ester (82185-45-3)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; at 0 ℃; for 3h;

DOI:10.1055/s-1982-29779

Reference yield:

bromoacetic acid tert-butyl ester (5292-43-3) → Phenylsulfamoyl-acetic acid tert-butyl ester (82185-45-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Zn, 3.) 20percent aq.NH₄Cl / 1.) dimethoxymethane, 2.) dimethoxymethane, room temp., 10 min.

2: 85 percent / m-chloroperbenzoic acid / CHCl₃ / 3 h / 0 °C

With ammonium chloride; 3-chloro-benzenecarboperoxoic acid; zinc; In chloroform;

DOI:10.1055/s-1982-29779

Reference yield:

N-phenylsulfinylamine (222851-56-1) → Phenylsulfamoyl-acetic acid tert-butyl ester (82185-45-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Zn, 3.) 20percent aq.NH₄Cl / 1.) dimethoxymethane, 2.) dimethoxymethane, room temp., 10 min.

2: 85 percent / m-chloroperbenzoic acid / CHCl₃ / 3 h / 0 °C

With ammonium chloride; 3-chloro-benzenecarboperoxoic acid; zinc; In chloroform;

DOI:10.1055/s-1982-29779

upstream raw materials:

t-butyl N-phenyl sulfinamoyl acetate

bromoacetic acid tert-butyl ester

N-phenylsulfinylamine