benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate

Base Information

• Chemical Name: benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate
• CAS No.: 59943-16-7
• Molecular Formula: C₃₁H₂₇NO₈
• Molecular Weight: 541.557
• Mol file: 59943-16-7.mol

Synonyms:benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate

Chemical Property of benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate

There total 3 articles about benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

monobenzyl phenylmalonate (25774-02-1) + Benzyl Clavulanate (57943-84-7) → benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate (59943-16-7)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; Ambient temperature;

Reference yield:

→ 2-Phenyl-malonic acid benzyl ester 2-[(2R,5R)-2-benzyloxycarbonyl-7-oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-(3E)-ylidene]-ethyl ester (59943-16-7)

Guidance literature:

Iso-Clavulaninsaere-benzylester (4), Phenylmalonsaeure-monobenzylester;

Reference yield:

→ 2-Phenyl-malonic acid benzyl ester 2-[2-benzyloxycarbonyl-7-oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-(3Z)-ylidene]-ethyl ester (59943-16-7)

Guidance literature:

aus Clavulansaeure ester I, Saeure V;

upstream raw materials:

monobenzyl phenylmalonate

Benzyl Clavulanate

Downstream raw materials:

9-O-clavulanic acid

Refernces