1-(4-chlorobenzyl)-3-chloromethyl-3-methyl-2-oxocyclopentanecarboxylic acid methyl ester

Base Information

Chemical Name:1-(4-chlorobenzyl)-3-chloromethyl-3-methyl-2-oxocyclopentanecarboxylic acid methyl ester
CAS No.:1415826-65-1
Molecular Formula:C₁₆H₁₈Cl₂O₃
Molecular Weight:329.223
Hs Code.:

Synonyms:1-(4-chlorobenzyl)-3-chloromethyl-3-methyl-2-oxocyclopentanecarboxylic acid methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-chlorobenzyl)-3-chloromethyl-3-methyl-2-oxocyclopentanecarboxylic acid methyl ester

Chemical Property:

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Technology Process of 1-(4-chlorobenzyl)-3-chloromethyl-3-methyl-2-oxocyclopentanecarboxylic acid methyl ester

There total 2 articles about 1-(4-chlorobenzyl)-3-chloromethyl-3-methyl-2-oxocyclopentanecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1311402-94-4
1-(4-chlorobenzyl)-3-methyl-3-hydroxymethyl-2-oxocyclopentanecarboxylic acid methyl ester

: 1415826-65-1
1-(4-chlorobenzyl)-3-chloromethyl-3-methyl-2-oxocyclopentanecarboxylic acid methyl ester

Guidance literature:: With thionyl chloride; N,N-dimethyl-formamide; In toluene; at 90 ℃; for 9h;

Reference yield:

: 1-[(4-chlorophenyl)methyl]-3-methyl-2-oxocyclopentanecarboxylic acid methyl ester

: 1415826-65-1
1-(4-chlorobenzyl)-3-chloromethyl-3-methyl-2-oxocyclopentanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: formaldehyd; potassium carbonate / water

2: thionyl chloride; sodium carbonate / water; N,N-dimethyl-formamide

With formaldehyd; thionyl chloride; sodium carbonate; potassium carbonate; In water; N,N-dimethyl-formamide;