4-Amino-3-ethoxycarbonyl-1-(1,3-dihydroxy-2-propoxy)methyl-2-methyl-5-phenylpyrrole

Base Information

Chemical Name:4-Amino-3-ethoxycarbonyl-1-(1,3-dihydroxy-2-propoxy)methyl-2-methyl-5-phenylpyrrole
CAS No.:205751-68-4
Molecular Formula:C₁₈H₂₄N₂O₅
Molecular Weight:348.399
Hs Code.:

Synonyms:4-Amino-3-ethoxycarbonyl-1-(1,3-dihydroxy-2-propoxy)methyl-2-methyl-5-phenylpyrrole

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Chemical Property of 4-Amino-3-ethoxycarbonyl-1-(1,3-dihydroxy-2-propoxy)methyl-2-methyl-5-phenylpyrrole

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Technology Process of 4-Amino-3-ethoxycarbonyl-1-(1,3-dihydroxy-2-propoxy)methyl-2-methyl-5-phenylpyrrole

There total 3 articles about 4-Amino-3-ethoxycarbonyl-1-(1,3-dihydroxy-2-propoxy)methyl-2-methyl-5-phenylpyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 205751-65-1
1-(1,3-Dihydroxy-2-propoxy)methyl-3-ethoxycarbonyl-2-methyl-4-nitro-5-phenylpyrrole

: 205751-68-4
4-Amino-3-ethoxycarbonyl-1-(1,3-dihydroxy-2-propoxy)methyl-2-methyl-5-phenylpyrrole

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 2585.7 Torr; Ambient temperature;

Reference yield:

: 37964-18-4
2-methyl-4-nitro-5-phenyl-pyrrole-3-carboxylic acid ethyl ester

: 205751-68-4
4-Amino-3-ethoxycarbonyl-1-(1,3-dihydroxy-2-propoxy)methyl-2-methyl-5-phenylpyrrole

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / NaH / acetonitrile / Ambient temperature

2: 70 percent / BCl₃ / CH₂Cl₂ / -78 - -70 °C

3: 70 percent / H₂ / 10percent Pd/C / ethanol / 2585.7 Torr / Ambient temperature

With hydrogen; boron trichloride; sodium hydride; palladium on activated charcoal; In ethanol; dichloromethane; acetonitrile;

Reference yield:

: 205751-57-1
1-(2-Benzyloxy-1-benzyloxymethyl-ethoxymethyl)-2-methyl-4-nitro-5-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester

: 205751-68-4
4-Amino-3-ethoxycarbonyl-1-(1,3-dihydroxy-2-propoxy)methyl-2-methyl-5-phenylpyrrole

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / BCl₃ / CH₂Cl₂ / -78 - -70 °C

2: 70 percent / H₂ / 10percent Pd/C / ethanol / 2585.7 Torr / Ambient temperature

With hydrogen; boron trichloride; palladium on activated charcoal; In ethanol; dichloromethane;