3-(2-Methoxy-5-methylphenyl)propan-1-ol

Base Information

Chemical Name:3-(2-Methoxy-5-methylphenyl)propan-1-ol
CAS No.:33538-80-6
Molecular Formula:C₁₁H₁₆O₂
Molecular Weight:180.247
Hs Code.:
NSC Number:105521
DSSTox Substance ID:DTXSID80295790
Wikidata:Q82035951

Synonyms:3-(2-methoxy-5-methylphenyl)propan-1-ol;33538-80-6;NSC 105521;NSC105521;DTXSID80295790;AKOS011888702;NSC-105521;EN300-1626426

Suppliers and Price of 3-(2-Methoxy-5-methylphenyl)propan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-(2-Methoxy-5-methylphenyl)propan-1-ol

Chemical Property:

Vapor Pressure:0.000967mmHg at 25°C
Boiling Point:290.2°C at 760 mmHg
Flash Point:120.7°C
Density:1.02g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:180.115029749
Heavy Atom Count:13
Complexity:136

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)OC)CCCO

Technology Process of 3-(2-Methoxy-5-methylphenyl)propan-1-ol

There total 7 articles about 3-(2-Methoxy-5-methylphenyl)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-Methoxy-5-methylphenylessigester

: 33538-80-6
3-(2-methoxy-5-methyl-phenyl)-propan-1-ol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 2h;
DOI:10.1002/anie.201705916

Reference yield:

: 92-47-7
3,4-dihydro-6-methyl-2H-1-benzopyran-2-one

: 33538-80-6
3-(2-methoxy-5-methyl-phenyl)-propan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether

2: aq. NaOH

With sodium hydroxide; lithium aluminium tetrahydride; In diethyl ether;
DOI:10.1002/jps.2600600815

Reference yield:

: 63113-79-1
methyl 2-methoxy-5-methylbenzoate

: 33538-80-6
3-(2-methoxy-5-methyl-phenyl)-propan-1-ol

Guidance literature:: Multi-step reaction with 5 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere

2.1: manganese(IV) oxide / tetrahydrofuran / 40 h / Inert atmosphere; Reflux

3.1: sodium hydride / tetrahydrofuran; mineral oil / 0.33 h / 23 °C / Inert atmosphere; Cooling with ice

3.2: 1 h / 0 - 23 °C / Inert atmosphere

4.1: palladium 10% on activated carbon; hydrogen / ethanol / 3 h / 23 °C / 760.05 Torr

5.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 °C

With manganese(IV) oxide; lithium aluminium tetrahydride; palladium 10% on activated carbon; hydrogen; sodium hydride; In tetrahydrofuran; ethanol; mineral oil;
DOI:10.1002/anie.201705916