4-{4-(4-fluorophenyl)-1-[1-(isoxazol-3-ylmethyl)piperidin-4-yl]-1H-imidazol-5-yl}pyrimidine hydrochloride

Base Information

Chemical Name:4-{4-(4-fluorophenyl)-1-[1-(isoxazol-3-ylmethyl)piperidin-4-yl]-1H-imidazol-5-yl}pyrimidine hydrochloride
CAS No.:1293395-69-3
Molecular Formula:C₂₂H₂₁FN₆O*ClH
Molecular Weight:440.908
Hs Code.:

Synonyms:4-{4-(4-fluorophenyl)-1-[1-(isoxazol-3-ylmethyl)piperidin-4-yl]-1H-imidazol-5-yl}pyrimidine hydrochloride

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Chemical Property of 4-{4-(4-fluorophenyl)-1-[1-(isoxazol-3-ylmethyl)piperidin-4-yl]-1H-imidazol-5-yl}pyrimidine hydrochloride

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Technology Process of 4-{4-(4-fluorophenyl)-1-[1-(isoxazol-3-ylmethyl)piperidin-4-yl]-1H-imidazol-5-yl}pyrimidine hydrochloride

There total 1 articles about 4-{4-(4-fluorophenyl)-1-[1-(isoxazol-3-ylmethyl)piperidin-4-yl]-1H-imidazol-5-yl}pyrimidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 89180-61-0
isoxazole-3-carboxaldehyde

: 1293396-31-2
4-[4-(4-Fluorophenyl)-1-piperidin-4-yl-1H-imidazol-5-yl]pyrimidine

: 1293395-69-3
4-{4-(4-fluorophenyl)-1-[1-(isoxazol-3-ylmethyl)piperidin-4-yl]-1H-imidazol-5-yl}pyrimidine hydrochloride

Guidance literature:: isoxazole-3-carboxaldehyde; 4-[4-(4-Fluorophenyl)-1-piperidin-4-yl-1H-imidazol-5-yl]pyrimidine; With sodium tris(acetoxy)borohydride; In tetrahydrofuran; for 18h;

With sodium hydrogencarbonate; In tetrahydrofuran; dichloromethane; water; pH=9 - 10;

With hydrogenchloride; In diethyl ether; ethyl acetate;