2-{3-[(4-fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethylamine

Base Information

• Chemical Name: 2-{3-[(4-fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethylamine
• CAS No.: 771474-10-3
• Molecular Formula: C₁₅H₁₄FN₃O₂S
• Molecular Weight: 319.359

Synonyms:2-{3-[(4-fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethylamine

Chemical Property of 2-{3-[(4-fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethylamine

Chemical Property:

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Technology Process of 2-{3-[(4-fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethylamine

There total 1 articles about 2-{3-[(4-fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2-(2-{3-[(4-fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethyl)-1H-isoindole-1,3(2H)-dione (1186403-52-0) → 2-{3-[(4-fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethylamine (771474-10-3)

Guidance literature:

With hydrazine; In 1,4-dioxane; at 20 - 40 ℃; for 20h;

DOI:10.1016/j.bmc.2009.05.055

Reference yield:

2-{3-[(4-fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethylamine (771474-10-3) → 2-{3-[(4-fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethylamine hydrochloride

Guidance literature:

With hydrogenchloride; In ethanol; water;

DOI:10.1016/j.bmc.2009.05.055

upstream raw materials:

2-(2-{3-[(4-fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethyl)-1H-isoindole-1,3(2H)-dione

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