(1R,2R)-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol

Base Information

• Chemical Name: (1R,2R)-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol
• CAS No.: 149022-18-4
• Molecular Formula: C29H50 N2 O3
• Molecular Weight: 474.728
• DSSTox Substance ID: DTXSID00164156
• Nikkaji Number: J641.739F
• Wikidata: Q27145141
• ChEMBL ID: CHEMBL1522805
• Mol file: 149022-18-4.mol

Synonyms:D-threo-PPMP;149022-18-4;(1R,2R)-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol;CHEBI:75126;N-[(1R,2R)-1-hydroxy-3-morpholin-4-yl-1-phenylpropan-2-yl]hexadecanamide;D,L-THREO-1-PHENYL-2-HEXADECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL;Hexadecanamide, N-((1R,2R)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl)-;Hexadecanamide, N-[(1R,2R)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-, rel-;Hexadecanoic acid ((1R,2R)-2-hydroxy-1-morpholin-4-ylmethyl-2-phenyl-ethyl)-amide;rel-N-[(1R,2R)-2-Hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-hexadecanamide;DL-threo-1-Phenyl-2-palmitoylamino-3-morpholino-1-propanol;(1R,threo)-PPMP;(R,R)-PPMP;CBiol_001749;BSPBio_001296;KBioGR_000016;KBioSS_000016;(1R,2R)-PPMP;SCHEMBL5452846;CHEMBL1522805;BCBcMAP01_000004;KBio2_000016;KBio2_002584;KBio2_005152;KBio3_000031;KBio3_000032;DTXSID00164156;Bio1_000035;Bio1_000524;Bio1_001013;Bio2_000016;Bio2_000496;HMS1791A18;HMS1989A18;HMS3402A18;AKOS040756730;HY-116535C;IDI1_033766;NCGC00161370-01;NCGC00161370-02;NCGC00161370-03;CS-0255236;Q27145141;(1R,2R)-3-morpholino-2-palmitoylamino-1-phenylpropan-1-ol;(R,R)-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol;D-threo-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol;(1R,2R)-2-hexadecanoylamino-3-morpholino-1-phenylpropan-1-ol;(1R,threo)-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol;DL-threo-1-Phenyl-2-palmitoylamino-3-morpholino-1-propanol, 98%;N-[(1R,2R)-1-hydroxy-3-(morpholin-4-yl)-1-phenylpropan-2-yl]palmitamide;N-[(1R,2R)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]hexadecanamide;N-[(1R,2R)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]palmitamide;N-[(1R,2R)-2-hydroxy-1-(morpholinomethyl)-2-phenyl-ethyl]hexadecanamide;D-threo-PPMP, 1R,2R-(+)-1-phenyl-2-palmitoylamino-3-N-morpholine-1-propanol, powder;Hexadecanamide, N-[(1R,2R)-2-hydroxy-1-(4-morpholinylmethyl)-2- phenylethyl]-;N-[(1R,2R)-1-hydroxy-3-(morpholin-4-yl)-1-phenylpropan-2-yl]hexadecanamide

Chemical Property of (1R,2R)-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol

Chemical Property:

• Vapor Pressure: 2.1E-17mmHg at 25°C
• Boiling Point: 642.8°Cat760mmHg
• Flash Point: 342.6°C
• PSA: 61.80000
• Density: 1.005g/cm³
• LogP: 7.14910
• Storage Temp.: 2-8°C
• XLogP3: 7.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 19
• Exact Mass: 474.38214346
• Heavy Atom Count: 34
• Complexity: 490

Purity/Quality:

99% ^*data from raw suppliers

DL-threo-1-Phenyl-2-palmitoylamino-3-morpholino-1-propanol 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCC(=O)NC(CN1CCOCC1)C(C2=CC=CC=C2)O
• Isomeric SMILES: CCCCCCCCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@@H](C2=CC=CC=C2)O
• Uses: DL-threo-PPMP Hydrochloride is a ceramide analog which inhibts glucosylceramide synthase. Used to study the role of glucosylceramide synthase in cell growth and apoptosis.

Technology Process of (1R,2R)-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol

There total 1 articles about (1R,2R)-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ DL-threo-1-phenyl-2-hexadecanoylamino-3-morpholino-1-propanol (149022-18-4)

Guidance literature: