diethyl (3S,5R)-5-hydroxy-2-[(S)-1-phenylethyl]isoxazolidinyl-3-phosphonate

Base Information

• Chemical Name: diethyl (3S,5R)-5-hydroxy-2-[(S)-1-phenylethyl]isoxazolidinyl-3-phosphonate
• CAS No.: 1018907-22-6
• Molecular Formula: C₁₅H₂₄NO₅P
• Molecular Weight: 329.333
• Mol file: 1018907-22-6.mol

Synonyms:diethyl (3S,5R)-5-hydroxy-2-[(S)-1-phenylethyl]isoxazolidinyl-3-phosphonate

Chemical Property of diethyl (3S,5R)-5-hydroxy-2-[(S)-1-phenylethyl]isoxazolidinyl-3-phosphonate

Chemical Property:

Purity/Quality:

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Technology Process of diethyl (3S,5R)-5-hydroxy-2-[(S)-1-phenylethyl]isoxazolidinyl-3-phosphonate

There total 1 articles about diethyl (3S,5R)-5-hydroxy-2-[(S)-1-phenylethyl]isoxazolidinyl-3-phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

diethyl (3S,5R)-5-acetoxy-2-[(S)-1-phenylethyl]isoxazolidinyl-3-phosphonate (1018907-19-1) → diethyl (3S,5R)-5-hydroxy-2-[(S)-1-phenylethyl]isoxazolidinyl-3-phosphonate (1018907-22-6) + diethyl (3S,5S)-5-hydroxy-2-[(S)-1-phenylethyl]isoxazolidinyl-3-phosphonate (1018907-23-7)

Guidance literature:

With ammonium hydroxide; In ethanol; at 20 ℃; for 2h;

DOI:10.1016/j.tetasy.2008.01.009

upstream raw materials:

diethyl (3S,5R)-5-acetoxy-2-[(S)-1-phenylethyl]isoxazolidinyl-3-phosphonate