2-oxohexahydrooxazo[5,4-c]pyridine-5(2H)-formic acid tert-butyl ester

Base Information

• Chemical Name: 2-oxohexahydrooxazo[5,4-c]pyridine-5(2H)-formic acid tert-butyl ester
• CAS No.: 1427170-53-3
• Molecular Formula: C₁₁H₁₈N₂O₄
• Molecular Weight: 242.275
• Mol file: 1427170-53-3.mol

Synonyms:2-oxohexahydrooxazo[5,4-c]pyridine-5(2H)-formic acid tert-butyl ester

Chemical Property of 2-oxohexahydrooxazo[5,4-c]pyridine-5(2H)-formic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-oxohexahydrooxazo[5,4-c]pyridine-5(2H)-formic acid tert-butyl ester

There total 1 articles about 2-oxohexahydrooxazo[5,4-c]pyridine-5(2H)-formic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C11H20N2O4 (1427170-50-0) → 2-oxohexahydrooxazo[5,4-c]pyridine-5(2H)-formic acid tert-butyl ester (1427170-53-3) + 4-amino-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester (203503-03-1,1331777-74-2,443955-98-4)

Guidance literature:

With sodium hypobromide; water; at 5 - 80 ℃; for 8h;

DOI:10.1016/j.bmcl.2013.01.048

Reference yield: 83.0%

2-oxohexahydrooxazo[5,4-c]pyridine-5(2H)-formic acid tert-butyl ester (1427170-53-3) + 2-methyl-[1,1’-biphenyl]-3-carboxylic acid (115363-11-6) → C25H28N2O5

Guidance literature:

With n-butyllithium; thionyl chloride; In tetrahydrofuran; at -78 - 20 ℃;

Reference yield: 47.0%

2-oxohexahydrooxazo[5,4-c]pyridine-5(2H)-formic acid tert-butyl ester (1427170-53-3) → C6H10N2O2*ClH (1427170-55-5)

Guidance literature:

With hydrogenchloride; In dichloromethane; at 20 ℃; for 3.5h;

DOI:10.1016/j.bmcl.2013.01.048

upstream raw materials:

C₁₁H₂₀N₂O₄

Downstream raw materials:

C₆H₁₀N₂O₂*ClH