N,N'-(1-(4-chlorophenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide)

Base Information

• Chemical Name: N,N'-(1-(4-chlorophenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide)
• CAS No.: 1374869-43-8
• Molecular Formula: C₁₂H₁₉ClN₂O₈S₄
• Molecular Weight: 483.008
• Mol file: 1374869-43-8.mol

Synonyms:N,N'-(1-(4-chlorophenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide)

Chemical Property of N,N'-(1-(4-chlorophenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-(1-(4-chlorophenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide)

There total 1 articles about N,N'-(1-(4-chlorophenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4-vinylbenzyl chloride (1073-67-2,24991-47-7) + dimesylamine (5347-82-0) → N,N'-(1-(4-chlorophenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide) (1374869-43-8)

Guidance literature:

With C₂₂H₃₅IN₂O₄; 3-chloro-benzenecarboperoxoic acid; In tert-butyl methyl ether; at 0 ℃; for 40h; Reagent/catalyst; Sealed tube;

DOI:10.1002/cssc.201900360

Reference yield:

N,N'-(1-(4-chlorophenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide) (1374869-43-8) → 1-(4-chlorophenyl)ethane-1,2-diamine (69810-94-2)

Guidance literature:

With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; at 0 - 85 ℃; for 15h;

DOI:10.1002/asia.201101025

Reference yield:

N,N'-(1-(4-chlorophenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide) (1374869-43-8) → N,N'-(1-(4-chlorophenyl)ethane-1,2-diyl)dibenzamide (1374869-53-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 15 h / 0 - 85 °C

2: triethylamine / 1 h / 25 °C

With triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene;

DOI:10.1002/asia.201101025

upstream raw materials:

4-vinylbenzyl chloride

dimesylamine

Downstream raw materials:

N,N'-(1-(4-chlorophenyl)ethane-1,2-diyl)dibenzamide

1-(4-chlorophenyl)ethane-1,2-diamine