5-amino-7-benzylseleno-8-cyano-3-ethoxycarbonyl-2-methyl-1,6-naphthyridine

Base Information

• Chemical Name: 5-amino-7-benzylseleno-8-cyano-3-ethoxycarbonyl-2-methyl-1,6-naphthyridine
• CAS No.: 328236-95-9
• Molecular Formula: C₂₀H₁₈N₄O₂Se
• Molecular Weight: 425.349
• Mol file: 328236-95-9.mol

Synonyms:5-amino-7-benzylseleno-8-cyano-3-ethoxycarbonyl-2-methyl-1,6-naphthyridine

Chemical Property of 5-amino-7-benzylseleno-8-cyano-3-ethoxycarbonyl-2-methyl-1,6-naphthyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-amino-7-benzylseleno-8-cyano-3-ethoxycarbonyl-2-methyl-1,6-naphthyridine

There total 3 articles about 5-amino-7-benzylseleno-8-cyano-3-ethoxycarbonyl-2-methyl-1,6-naphthyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

5-amino-7-benzylselanyl-8-cyano-4-furan-2-yl-2-methyl-1,4-dihydro-[1,6]naphthyridine-3-carboxylic acid ethyl ester (280573-96-8) → 5-amino-7-benzylseleno-8-cyano-3-ethoxycarbonyl-2-methyl-1,6-naphthyridine (328236-95-9)

Guidance literature:

With acetic acid; for 1h; Heating;

DOI:10.1023/A:1009593622244

Reference yield:

benzyl chloride (100-44-7) → 5-amino-7-benzylseleno-8-cyano-3-ethoxycarbonyl-2-methyl-1,6-naphthyridine (328236-95-9)

Guidance literature:

Multi-step reaction with 2 steps

1: N-methylmorpholine / ethanol / 20 °C

2: 65 percent / NaNO₂; H₂SO₄ / acetic acid / 0.08 h / 18 - 22 °C

With 4-methyl-morpholine; sulfuric acid; sodium nitrite; In ethanol; acetic acid;

Reference yield:

(Z)-1-(α-Furyl)-2-ethoxycarbonyl-1-buten-3-one (17448-84-9,61800-71-3,61712-97-8) → 5-amino-7-benzylseleno-8-cyano-3-ethoxycarbonyl-2-methyl-1,6-naphthyridine (328236-95-9)

Guidance literature:

Multi-step reaction with 2 steps

1: N-methylmorpholine / ethanol / 20 °C

2: 65 percent / NaNO₂; H₂SO₄ / acetic acid / 0.08 h / 18 - 22 °C

With 4-methyl-morpholine; sulfuric acid; sodium nitrite; In ethanol; acetic acid;

upstream raw materials:

5-amino-7-benzylselanyl-8-cyano-4-furan-2-yl-2-methyl-1,4-dihydro-[1,6]naphthyridine-3-carboxylic acid ethyl ester

benzyl chloride

(Z)-1-(α-Furyl)-2-ethoxycarbonyl-1-buten-3-one